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[儿童阻塞性睡眠呼吸暂停]

[Obstructive sleep apnea in children].

作者信息

Fagondes Simone Chaves, Moreira Gustavo Antonio

机构信息

Serviço de Pneumologia, Laboratório do Sono, Hospital de Clinicas de Porto Alegre, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.

出版信息

J Bras Pneumol. 2010 Jun;36 Suppl 2:57-61. doi: 10.1590/s1806-37132010001400015.

Abstract

Childhood obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of partial or complete upper airway obstruction during sleep. The disease encompasses a continuum from primary snoring (a benign condition without physiological alterations or associated complications) to increased upper airway resistance, obstructive hypoventilation and OSAS. The prevalence of snoring is high, ranging from 1.5% to 15%, depending on how it is defined. Based on parent-reported questionnaires and complementary tests, the prevalence of OSAS is 1-4%. This syndrome is more common in boys, overweight children, of African ancestry, with a history of atopy and prematurity. The most common symptoms are snoring that is frequent and loud; family-reported apnea; and restless sleep. The physical examination should assess growth status, signs of chronic upper airway obstruction, and craniofacial malformations. Overnight polysomnography is the gold standard test for the diagnosis and for the determination of the appropriate positive pressure level, as well as for postsurgical treatment evaluation. Intermittent hypoxia and multiple arousals resulting from obstructive events contribute to the well-described cardiovascular, neurocognitive, and behavioral consequences in pediatric patients with OSAS. Although the main treatment for OSAS in children is adenotonsillectomy, treatment with CPAP or Bilevel is becoming more widely used in the pediatric population.

摘要

儿童阻塞性睡眠呼吸暂停综合征(OSAS)的特征是睡眠期间反复出现部分或完全上呼吸道阻塞发作。该疾病涵盖了从原发性打鼾(一种无生理改变或相关并发症的良性状况)到上呼吸道阻力增加、阻塞性通气不足和OSAS的连续过程。打鼾的患病率很高,根据定义方式的不同,在1.5%至15%之间。根据家长报告的问卷和补充检查,OSAS的患病率为1%-4%。该综合征在男孩、超重儿童、非洲裔儿童、有特应性病史和早产史的儿童中更为常见。最常见的症状是频繁且响亮的打鼾、家人报告的呼吸暂停以及睡眠不安。体格检查应评估生长状况、慢性上呼吸道阻塞的体征和颅面畸形。夜间多导睡眠图是诊断、确定合适的正压水平以及术后治疗评估的金标准检查。阻塞性事件导致的间歇性缺氧和多次觉醒会导致OSAS患儿出现众所周知的心血管、神经认知和行为后果。虽然儿童OSAS的主要治疗方法是腺样体扁桃体切除术,但持续气道正压通气(CPAP)或双水平气道正压通气(Bilevel)治疗在儿科人群中的应用越来越广泛。

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