通过聚合酶链反应确认牛κ-酪蛋白基因座的定位

Confirmation of assignment of the bovine K-casein locus by PCR.

作者信息

Monteagudo L V, Tejedor M T, Arruga M V, Mazhar K, Pinder S J, Savva D, Skidmore C J

机构信息

Departamento de Anatomia, Embriologia y Genetica, Facultad de Veterinaria, Universidad de Zaragoza, Spain.

出版信息

Res Vet Sci. 1992 Mar;52(2):264-5. doi: 10.1016/0034-5288(92)90022-t.

DOI:10.1016/0034-5288(92)90022-t

PMID:1585084

Abstract

The provision of a bovine gene map will allow the ready identification of genetic disease in cattle and will lead to the identification of the genetic loci responsible for quantitative traits of economic importance. An extension of the polymerase chain reaction to the identification of linkage in bovine-Chinese hamster cell hybrids has improved the speed and facility of the assignment of genes to linkage groups and thus makes it easier to achieve a bovine linkage map.

摘要

牛基因图谱的提供将有助于快速识别牛的遗传疾病，并将有助于识别与具有经济重要性的数量性状相关的基因位点。将聚合酶链反应扩展到牛 - 中国仓鼠细胞杂种中的连锁鉴定，提高了将基因分配到连锁群的速度和便利性，从而使构建牛连锁图谱更加容易。