Valderrábano Miguel, Cesario David A, Ji Sen, Shannon Kevin, Wiener Isaac, Swerdlow Charles D, Oral Hakan, Morady Fred, Shivkumar Kalyanam
UCLA Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Heart Rhythm. 2004 Sep;1(3):311-6. doi: 10.1016/j.hrthm.2004.03.073.
The aim of this study was to define the role of percutaneous epicardial mapping for the ablation of previous failed ablation of accessory pathways.
Cardiac surgery is the only curative option for failed radiofrequency (RF) catheter ablation of accessory pathway (AP)-mediated tachycardias. We investigated a combined percutaneous epicardial and endocardial approach for failed AP ablations.
We present our experience in a series of 6 cases (7 APs) with previous failed attempts at catheter ablation (median 2 attempts, range 1-4) and persistent symptomatic tachycardias. Endocardial mapping of the APs was performed using conventional techniques. Sites with local electrograms suggestive of AP location were selected. When initial endocardial mapping was not successful for ablation of the pathway, percutaneous transthoracic pericardial puncture was performed via a subxiphoid approach, and an ablation catheter was positioned at the epicardial aspect of the putative AP location for epicardial-endocardial electrogram comparison. Endocardial RF energy was applied to locations considered appropriate. Epicardial RF applications were delivered when endocardial applications failed. Coronary arteriography was performed to assess the proximity of coronary arteries to the ablation catheter.
APs were located in the right free wall (4 patients, 5 APs) and the right (1 patient) and left (1 patient) posteroseptal regions. In all patients, epicardial mapping assisted in identifying successful ablation sites. In 3 patients, the earliest atrial activation during orthodromic tachycardia was present in an epicardial electrogram. Successful AP ablation was achieved with an epicardial RF application in 2 patients, either alone or with simultaneous endocardial-epicardial delivery. In the remaining 4 patients, APs were successfully ablated endocardially after epicardial mapping. These patients represent 18% of all cases referred to our institution for ablation of previously failed accessory pathways (6/32 patients).
A combined endocardial-epicardial approach to mapping and RF ablation can facilitate successful endocardial ablation in most cases. In selected cases, APs can be ablated by epicardial delivery of RF. Epicardial mapping is an effective alternative to cardiac surgery for patients in whom prior attempts at AP ablation have failed.
本研究旨在明确经皮心外膜标测在既往旁路消融失败后的消融治疗中的作用。
心脏手术是射频(RF)导管消融旁路(AP)介导的心动过速失败后的唯一治愈选择。我们研究了一种经皮心外膜和心内膜联合方法用于AP消融失败的情况。
我们介绍了一系列6例(7条AP)患者的经验,这些患者既往导管消融尝试失败(中位数2次,范围1 - 4次)且持续性有症状心动过速。使用传统技术对AP进行心内膜标测。选择局部电图提示AP位置的部位。当初始心内膜标测不能成功消融该旁路时,经剑突下途径进行经皮经胸心包穿刺,并将消融导管置于推测的AP位置的心外膜面以进行心外膜 - 心内膜电图比较。在心内膜认为合适的位置施加RF能量。当心内膜消融失败时进行心外膜RF消融。进行冠状动脉造影以评估冠状动脉与消融导管的接近程度。
AP位于右游离壁(4例患者,5条AP)以及右(1例患者)和左(1例患者)后间隔区域。在所有患者中,心外膜标测有助于确定成功的消融部位。在3例患者中,正向性心动过速期间最早的心房激动出现在心外膜电图中。2例患者单独或同时进行心内膜 - 心外膜消融时,通过心外膜RF消融成功消融了AP。在其余4例患者中,在心外膜标测后经心内膜成功消融了AP。这些患者占转诊至我院进行既往失败的旁路消融的所有病例的18%(6/32例患者)。
心内膜 - 心外膜联合标测和RF消融方法在大多数情况下可促进心内膜消融成功。在特定病例中,可通过心外膜施加RF消融AP。对于既往AP消融尝试失败的患者,心外膜标测是心脏手术的有效替代方法。