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用于生理血流模拟的血液流变学模型比较。

Comparison of blood rheological models for physiological flow simulation.

作者信息

Neofytou Panagiotis

机构信息

Environmental Research Laboratory, Institute of Nuclear Technology and Radiation Protection, National Centre for Scientific Research Demokritos, Agia Paraskevi, 15310 Athens, Greece.

出版信息

Biorheology. 2004;41(6):693-714.

Abstract

The present study investigates the flow effects that different blood constitutive equations induce when employed in numerical simulations in the framework of computational hemodynamics. In accord with experimental studies on the rheological behavior of blood, three blood constitutive equations namely the Casson, Power-Law and Quemada models were used for simulating the shear flow behavior of blood. The case studied is the flow in a channel with a moving part of the boundary and was selected because it reproduces the flow phenomena occurring in realistic arterial conditions. Flow simulation for every model is carried out assuming the same flow rate at the inlet of the channel and different Strouhal numbers reflecting different intensities of the boundary movement. Results show that the modeling of blood as non-Newtonian fluid has marked qualitative and quantitative effects on both the flow field and the wall shear stress whereas comparison of the different models shows good agreement between the flow effects by the Casson and Quemada models.

摘要

本研究探讨了在计算血液动力学框架下进行数值模拟时,不同血液本构方程所引起的流动效应。根据对血液流变行为的实验研究,使用了三个血液本构方程,即卡森模型、幂律模型和凯马达模型来模拟血液的剪切流动行为。所研究的案例是具有运动边界部分的通道内的流动,选择该案例是因为它再现了实际动脉条件下发生的流动现象。对每个模型进行流动模拟时,假设通道入口处的流量相同,并采用不同的斯特劳哈尔数来反映边界运动的不同强度。结果表明,将血液建模为非牛顿流体对流场和壁面剪应力都有显著的定性和定量影响,而不同模型的比较表明,卡森模型和凯马达模型的流动效应之间具有良好的一致性。

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