Neofytou Panagiotis, Tsangaris Sokrates, Kyriakidis Michalis
Thermal-Hydraulics and Multiphase Flow Laboratory, INT-RP, NCSR Demokritos, Athens, Greece.
Comput Methods Biomech Biomed Engin. 2008 Dec;11(6):615-26. doi: 10.1080/10255840802214999.
The current study is focused on the numerical investigation of the flow field induced by the unsteady flow in the vicinity of an abdominal aortic aneurysm model. The computational fluid dynamics code used is based on the finite volume method, and it has already been used in various bioflow studies. For modelling the rheological behaviour of blood, the Quemada non-Newtonian model is employed, which is suitable for simulating the two-phase character of blood namely a suspension of blood cells in plasma. For examining its non-Newtonian effects a comparison with a corresponding Newtonian flow is carried out. Furthermore, the investigation is focused on the distribution of the flow-induced forces on the interior wall of the aneurysm and in order to study the development of the distribution with the gradual enlargement of the aneurysm, three different degrees of aneurysm-growth have been assumed. Finally and for examining the effect of the distribution on the aneurysm growth, a comparison is made between the pressure and wall shear-stress distributions at the wall for each growth-degree.
当前的研究聚焦于腹主动脉瘤模型附近非定常流动所诱导的流场的数值研究。所使用的计算流体动力学代码基于有限体积法，并且已经在各种生物流体研究中得到应用。为了模拟血液的流变行为，采用了Quemada非牛顿模型，该模型适用于模拟血液的两相特性，即血细胞在血浆中的悬浮液。为了研究其非牛顿效应，与相应的牛顿流进行了比较。此外，研究集中在动脉瘤内壁上流动诱导力的分布，并且为了研究随着动脉瘤逐渐增大分布的发展情况，假定了三种不同程度的动脉瘤生长。最后，为了研究该分布对动脉瘤生长的影响，对每种生长程度下动脉瘤壁处的压力和壁面剪应力分布进行了比较。
