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一项针对痴呆症患者的维持性认知刺激疗法(MCST)有效性的试点研究。

A pilot study examining the effectiveness of maintenance Cognitive Stimulation Therapy (MCST) for people with dementia.

作者信息

Orrell Martin, Spector Aimee, Thorgrimsen Lene, Woods Bob

机构信息

Department of Mental Health Sciences, University College London, UK.

出版信息

Int J Geriatr Psychiatry. 2005 May;20(5):446-51. doi: 10.1002/gps.1304.

Abstract

BACKGROUND

A recent randomised controlled trial on Cognitive Stimulation Therapy (CST) identified the need to evaluate its more long-term benefits for people with dementia. This study evaluates the effectiveness of a weekly maintenance CST programme for people with dementia in residential care.

METHOD

Thirty-five people with dementia were included, following on from a seven-week twice-weekly study of CST. The maintenance CST sessions ran in two residential homes using a once a week programme of CST over an additional 16 weeks. Two control homes did not receive the maintenance intervention.

RESULTS

Using repeated measures ANOVAS, there was a continuous, significant improvement in cognitive function (MMSE) for those receiving MCST (CST+maintenance CST sessions) as compared to CST alone or no treatment (p = 0.012). There were no effects on quality of life, behaviour or communication following maintenance sessions. The initial cognitive improvements following CST were only sustained at follow-up when followed by the programme of maintenance CST sessions.

CONCLUSIONS

The cognitive benefits of CST can be maintained by weekly sessions for around 6 months. A large-scale, multi-centre maintenance CST trial is required to clarify potential longer-term benefits of maintenance CST for dementia.

摘要

背景

最近一项关于认知刺激疗法(CST)的随机对照试验表明,有必要评估其对痴呆症患者更长期的益处。本研究评估了针对住院护理痴呆症患者的每周一次维持性CST计划的有效性。

方法

在一项为期七周、每周两次的CST研究之后,纳入了35名痴呆症患者。维持性CST课程在两个养老院进行,采用每周一次的CST计划,为期16周。两个对照养老院未接受维持性干预。

结果

使用重复测量方差分析,与单独接受CST或不接受治疗相比,接受MCST(CST+维持性CST课程)的患者认知功能(MMSE)持续显著改善(p = 0.012)。维持性课程对生活质量、行为或沟通没有影响。CST后的初始认知改善仅在后续进行维持性CST课程时在随访中得以维持。

结论

CST的认知益处可通过每周一次的课程维持约6个月。需要进行大规模、多中心的维持性CST试验,以阐明维持性CST对痴呆症潜在的长期益处。

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