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医疗保健经济评估的未来挑战:患者偏好、风险态度及其他。

Future challenges for the economic evaluation of healthcare: patient preferences, risk attitudes and beyond.

作者信息

Bridges John F P

机构信息

Department of Tropical Hygiene and Public Health, University of Heidelberg-Medical School, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany.

出版信息

Pharmacoeconomics. 2005;23(4):317-21. doi: 10.2165/00019053-200523040-00002.

Abstract

The continued growth in the economic evaluation of healthcare over the past 25 years has led to a shortage of trained health economists globally, leading to a number of universities and/or national governments developing specialised health economics programmes to train more health economists. One of the common problems with many of these training programmes is that they only educate new health economists to the Masters level, and as such they are unable to cover the many skills needed by a successful health economist. Furthermore, government and industry interests have ensured that economic evaluation is a heavily regulated environment that gives little incentive to seek further education. These two related factors (under-education and over-regulation) have lead to a situation where economic evaluation methods may adversely limit innovation of therapeutics and devices in clinical areas that perform badly when evaluated on the cost per QALY scale. The good news, however, is that the tide is turning and theoretically sound adjustments (such as risk adjustments and stated preferences) to the current paradigm are now being considered. This, of cause, is just the tip of the iceberg with other important issues such as time preference and the endogeneity of preference remaining very much under-researched areas in health. This paper concludes that many of these real-world issues, such as patient preferences, can be avoided by using artificial objective functions such as cost per QALY, but this comes at the cost of irrelevance and the misallocation of resources. If we are to meet all of the future challenges in economic evaluation in healthcare then we must focus more on advanced education and far less on the regulation of health economists.

摘要

在过去25年里,医疗保健经济评估的持续增长导致全球范围内训练有素的卫生经济学家短缺,这促使许多大学和/或国家政府制定专门的卫生经济学课程,以培养更多的卫生经济学家。许多此类培训项目的一个常见问题是,它们只将新的卫生经济学家培养到硕士水平,因此无法涵盖一名成功的卫生经济学家所需的多种技能。此外,政府和行业利益确保了经济评估是一个受到严格监管的环境,几乎没有激励人们寻求进一步的教育。这两个相关因素(教育不足和监管过度)导致了一种情况,即经济评估方法可能会对临床领域治疗方法和设备的创新产生不利限制,而这些领域在按每质量调整生命年(QALY)成本进行评估时表现不佳。然而,好消息是情况正在发生转变,目前正在考虑对当前范式进行理论上合理的调整(如风险调整和陈述性偏好)。当然,这只是冰山一角,诸如时间偏好和偏好的内生性等其他重要问题在卫生领域仍然是研究非常不足的领域。本文的结论是,许多这些现实世界的问题,如患者偏好,可以通过使用人工目标函数(如每QALY成本)来避免,但这是以相关性丧失和资源分配不当为代价的。如果我们要应对医疗保健经济评估未来的所有挑战,那么我们必须更多地关注高等教育,而更少地关注对卫生经济学家的监管。

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