Garcia-Manero Guillermo, Glantz Michael
Department of Leukemia, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard Houston, TX 77030, USA.
Expert Rev Neurother. 2004 Jul;4(4 Suppl):S25-31. doi: 10.1586/14737175.4.4.S25.
The final subject to be addressed is the role of prophylactic treatment for hematologic tumors. Prophylactic intrathecal therapy is the standard of care in pediatric acute lymphocytic leukemia patients. Should prophylaxis be applied to adult patients with leukemia? In addition and as an extension of the adult leukemia patient discussion, is there a role for intrathecal prophylaxis in patients with lymphoma, a population at risk for neoplastic meningitis?
最后要讨论的主题是血液肿瘤的预防性治疗的作用。鞘内预防性治疗是小儿急性淋巴细胞白血病患者的标准治疗方法。对于成年白血病患者是否应进行预防性治疗？此外，作为成年白血病患者讨论的延伸，对于淋巴瘤患者（有发生肿瘤性脑膜炎风险的人群），鞘内预防性治疗是否有作用？
