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严重人工瓣膜心内膜炎的主动脉瓣移位术:早期结果与长期随访

Aortic valve translocation for severe prosthetic valve endocarditis: early results and long-term follow-up.

作者信息

Nottin Rémi, Al-Attar Nawwar, Ramadan Ramzi, Azmoun Alexandre, Therasse Alexis, Kortas Chokri, Ly Mohamedou, Bouchachi Amir, Bourachot-Montantême Marie-Laure

机构信息

Department of Adult Cardiovascular Surgery, Marie-Lannelongue Hospital, Le Plessis-Robinson, France.

出版信息

Ann Thorac Surg. 2005 May;79(5):1486-90. doi: 10.1016/j.athoracsur.2004.10.047.

Abstract

BACKGROUND

Surgical management of ventriculo-aortic disconnection and aortic root abscesses after prosthetic aortic valve endocarditis carries high mortality and morbidity. Initial experience with translocation of the aortic valve and distal coronary artery bypass grafting was disappointing in terms of short-term and long-term success in the few published reports. We describe a technique of translocation of the aortic valve into the ascending aorta with direct antegrade myocardial revascularization.

METHODS

Between 1980 and 1992, we included 21 patients and evaluated their long-term outcome. The surgical technique included extracting the aortic valve prosthesis, resecting all infected tissue, restoring the left ventricular outflow tract, and translocating the aortic valve into the ascending aorta, associated with myocardial revascularization of the left main trunk and the proximal right coronary artery.

RESULTS

All patients required emergency surgery: 15 patients were in severe congestive heart failure, 3 patients were in cardiogenic shock, and 3 patients had multiple neurologic and peripheral signs of distal embolization. Fifteen patients had active prosthetic valve endocarditis. Intraoperative findings dictated the translocation. The overall hospital mortality was 14%. None of the 18 hospital survivors had prosthetic aortic valve endocarditis recurrence. All patients were observed from 12 to 22 years, are alive, and have resumed normal activities.

CONCLUSIONS

In severe forms of prosthetic valve endocarditis, this technique provides a safe and reliable alternative to homograft replacement. The long-term results are satisfactory.

摘要

背景

人工主动脉瓣心内膜炎后心室-主动脉离断和主动脉根部脓肿的外科治疗具有较高的死亡率和发病率。在少数已发表的报告中,主动脉瓣移位及远端冠状动脉旁路移植术在短期和长期成功率方面的初步经验并不理想。我们描述了一种将主动脉瓣移位至升主动脉并直接进行顺行心肌血运重建的技术。

方法

1980年至1992年间,我们纳入了21例患者并评估了他们的长期预后。手术技术包括取出主动脉瓣人工瓣膜、切除所有感染组织、恢复左心室流出道,以及将主动脉瓣移位至升主动脉,同时对左主干和右冠状动脉近端进行心肌血运重建。

结果

所有患者均需急诊手术:15例患者处于严重充血性心力衰竭状态,3例患者处于心源性休克状态,3例患者有远端栓塞的多种神经和外周体征。15例患者有活动性人工瓣膜心内膜炎。术中发现决定了移位操作。总体医院死亡率为14%。18例医院幸存者中无一例人工主动脉瓣心内膜炎复发。所有患者均接受了12至22年的观察,均存活且已恢复正常活动。

结论

在严重形式的人工瓣膜心内膜炎中,该技术为同种异体移植替代提供了一种安全可靠的选择。长期结果令人满意。

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