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机械人工心脏瓣膜保留术治疗感染性心内膜炎合并主动脉根部脓肿。

Mechanical Prosthetic Valve Sparing for Aortic Root Abscess Complicated by Infective Endocarditis.

机构信息

Department of Cardiothoracic Surgery, Faculty of Medicine, Ain Shams University, 11517 Cairo, Egypt.

出版信息

Tex Heart Inst J. 2020 Aug 1;47(4):280-283. doi: 10.14503/THIJ-19-7059.

Abstract

Aortic root abscess complicated by infective endocarditis of a mechanical prosthetic valve is associated with morbidity and death. We retrospectively report our experience with a valve-sparing technique for managing this condition. From October 2014 through November 2017, 41 patients at our center underwent surgery for aortic root abscess complicated by infective endocarditis of a mechanical prosthetic valve. Twenty (48.7%) met prespecified criteria for use of our valve-sparing technique after careful assessment of the mechanical valve and surrounding tissues. Our technique involved draining the abscess, aggressively débriding all infected and necrotic tissues, and then repairing the resulting defect by suturing a Gelweave patch to the healthy aortic wall and to the cuff of the valve. We successfully preserved the mechanical aortic valve in all 20 patients. Two (10%) died early (≤30 d postoperatively) of low cardiac output syndrome with progressive heart failure, superadded septicemia, and multisystem organ failure. At 1-year follow-up, the 18 surviving patients (90%) were symptom free and had a well-functioning mechanical aortic valve with no paravalvular leak. We conclude that, in certain patients, our technique for managing aortic root abscess and sparing the mechanical aortic valve is a safe and less time-consuming approach with relatively low mortality and encouraging midterm follow-up outcomes.

摘要

主动脉根部脓肿合并机械人工心脏瓣膜感染性心内膜炎可导致发病率和死亡率升高。我们回顾性报告了使用保留瓣膜技术治疗这种疾病的经验。2014 年 10 月至 2017 年 11 月,我们中心的 41 名患者因主动脉根部脓肿合并机械人工心脏瓣膜感染性心内膜炎而接受手术治疗。经过仔细评估机械瓣膜和周围组织,20 名(48.7%)符合我们保留瓣膜技术的预设标准。我们的技术包括引流脓肿,积极清创所有感染和坏死组织,然后通过将 Gelweave 补丁缝合到健康的主动脉壁和瓣膜袖口来修复由此产生的缺陷。我们成功地在所有 20 名患者中保留了机械主动脉瓣膜。2 名(10%)患者在术后早期(≤30 天)死于低心输出量综合征伴进行性心力衰竭、继发败血症和多器官功能衰竭。在 1 年的随访中,18 名存活患者(90%)无症状,机械主动脉瓣膜功能良好,无瓣周漏。我们得出结论,在某些患者中,我们治疗主动脉根部脓肿并保留机械主动脉瓣膜的技术是一种安全且耗时更少的方法,死亡率相对较低,中期随访结果令人鼓舞。

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