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血管网络建模

Modeling of vascular networks.

作者信息

Dawson Thomas H

机构信息

United States Naval Academy, 590 Holloway Road, Annapolis, MD, 21402, USA.

出版信息

J Exp Biol. 2005 May;208(Pt 9):1687-94. doi: 10.1242/jeb.01622.

Abstract

Vascular networks refer here mainly to the microscale capillary networks of the vascular system of mammals, although they may also be considered to include the small arteries that feed the capillaries and the small veins that drain them. The modeling of these networks for resting mammals is reviewed within the context of describing related scaling laws for mammals of vastly different size. Basic processes are considered and alternative approaches mentioned. All lead to the same scaling laws for the radius, length and number of the vessels. The applicability of the relations is illustrated using existing measurements. Discussion is also included on the effect of strenuous exercise on the scaling law for number of capillary vessels and matters related to it.

摘要

这里的血管网络主要指哺乳动物血管系统的微观毛细血管网络,不过也可以认为其包括为毛细血管供血的小动脉以及引流血液的小静脉。在描述不同体型哺乳动物相关标度律的背景下,回顾了静止状态下哺乳动物这些网络的建模情况。考虑了基本过程并提及了替代方法。所有这些都得出了关于血管半径、长度和数量的相同标度律。利用现有测量结果说明了这些关系的适用性。还讨论了剧烈运动对毛细血管数量标度律的影响及其相关问题。

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