Hersh Marla R, Choi Junsung, Garrett Chris, Clark Robert
Department of Radiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612-9497, USA.
Cancer Control. 2005 Apr;12(2):111-5. doi: 10.1177/107327480501200206.
Because of the recent reclassification of mesenchymal tumors, which was based on a better understanding of the genetics and immunophenotype of gastrointestinal stromal tumors (GISTs), only a limited number of studies have described the radiologic appearance of GISTs.
This study reviews the imaging characteristics of GISTs, with an emphasis on differentiating benign and malignant tumors using positron emission tomography (PET), computed tomography (CT), and magnetic resonance imaging (MRI). We reviewed the data from 53 cases of GISTs treated at our institute. The imaging studies from these cases, which were recorded at our institute from January 1998 through June 2003, included PET, CT, and MRI.
Of the 53 GIST cases, stomach and small bowel tumors accounted for 80% of the tumors. Malignant lesions were larger and more heterogeneous, had ulcerations, and were PET positive. Peritoneal and liver metastases were most common.
PET, CT, and MRI appear to be useful in differentiating nonmetastasizing from malignant GISTs.
由于最近基于对胃肠道间质瘤（GIST）遗传学和免疫表型的更好理解对间充质肿瘤进行了重新分类，仅有有限数量的研究描述了GIST的放射学表现。
本研究回顾了GIST的影像学特征，重点是使用正电子发射断层扫描（PET）、计算机断层扫描（CT）和磁共振成像（MRI）鉴别良性和恶性肿瘤。我们回顾了在我院接受治疗的53例GIST患者的数据。这些病例于1998年1月至2003年6月在我院进行记录，其影像学检查包括PET、CT和MRI。
在53例GIST病例中，胃和小肠肿瘤占肿瘤的80%。恶性病变更大且更不均匀，有溃疡，PET呈阳性。腹膜和肝转移最为常见。
PET、CT和MRI似乎有助于鉴别非转移性和恶性GIST。
