Howell Peter B, Mott David R, Fertig Stephanie, Kaplan Carolyn R, Golden Joel P, Oran Elaine S, Ligler Frances S
Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington DC, 20375-5348, USA.
Lab Chip. 2005 May;5(5):524-30. doi: 10.1039/b418243j. Epub 2005 Apr 13.
A new microfluidic mixer is presented consisting of a rectangular channel with grooves placed in the top and bottom. This not only increases the driving force behind the lateral flow, but allows for the formation of advection patterns that cannot be created with structures on the bottom alone. Chevrons, pointing in opposite directions on the top and bottom, are used to create a pair of vortices positioned side by side. Stripes running the width of the channel generate a pair of vertically stacked vortices. Computational fluid dynamics (CFD) simulations are used to model the behavior of the systems and provide velocity maps at cross-sections within the mixer. Experiments demonstrate the mixing that results when two segregated species enter the mixer side-by-side and pass through two cycles of the mixer (i.e., two alternating sets of four stripes and four chevrons).
本文介绍了一种新型微流体混合器，它由一个在顶部和底部设有凹槽的矩形通道组成。这不仅增加了横向流动背后的驱动力，还能形成仅靠底部结构无法产生的平流模式。顶部和底部指向相反方向的人字形图案用于产生一对并排的涡流。沿通道宽度方向的条纹产生一对垂直堆叠的涡流。计算流体动力学（CFD）模拟用于对系统行为进行建模，并提供混合器内横截面处的速度图。实验展示了两种分离的物质并排进入混合器并经过混合器的两个循环（即两组交替的四条条纹和四个人字形图案）时所产生的混合效果。
