Handojo I
Int J Dermatol. 1979 Jul-Aug;18(6):489-96. doi: 10.1111/j.1365-4362.1979.tb01956.x.
A clinical trial using tretinoin lotion 0.05%, benzoyl peroxide 5% and 10% as topical application was performed on 250 ambulatory patients suffering from various degrees of acne vulgaris. The results indicate that tretinoin applied in the morning and benzoyl peroxide applied at night is the most efficacious regimen to be used, with minimal side effects.
对250名患有不同程度寻常痤疮的门诊患者进行了一项临床试验,外用0.05%维甲酸洗剂、5%和10%过氧化苯甲酰。结果表明,早上使用维甲酸,晚上使用过氧化苯甲酰是最有效的治疗方案,且副作用最小。