Tsushima Yoshito, Endo Keigo
Department of Radiology, Motojima General Hospital, 3-8 Nishi-Honcho, Ohta, Gunma 373-0033, Japan.
Radiology. 2005 May;235(2):575-9. doi: 10.1148/radiol.2352032121.
To evaluate ability of magnetic resonance (MR) imaging to depict an abnormality in patients with chronic or recurrent headache without neurologic abnormality.
Institutional review board approval and patient informed consent were not required. A total of 306 patients with normal neurologic findings and chronic or recurrent headache were examined with MR imaging. Patients were divided into three groups: those with no abnormality, those with minor abnormality, and those with clinically important intracranial abnormality, which may result in chronic or recurrent headache. Literature review was also performed. Upper 99.5% confidence bound for frequency of abnormal MR findings was calculated.
A total of 169 patients (55.2%) were placed in the first group, 135 (44.1%) were placed in the second group, and two (0.7%) were placed in the third group because they had a clinically important abnormality at MR imaging. Neither contrast material enhancement (n = 195) nor repeated MR imaging (n = 23) contributed to the diagnosis. Literature review revealed two previous studies concerning unspecified headache (in addition to the current study), including a total of 1036 MR imaging results and 22 (2.1%) clinically important results (upper 99.5% confidence bound, 3.4%). Twelve studies of migraine headache were found, with a total of 790 MR imaging examinations. Excluding the 19 patients with complicated migraine, the 99.5% confidence bound of the frequency of clinically important abnormality at MR imaging was estimated as 0.68%. Clinically important infarctions were noted on MR images in five (26.3%) of 19 patients with complicated migraine.
MR imaging is an unrewarding technique in the evaluation of patients with chronic or recurrent headache and normal neurologic findings. Neither contrast enhancement nor repeated MR imaging contributed to diagnosis, although the number of patients in the latter category was small.
评估磁共振(MR)成像描绘无神经功能异常的慢性或复发性头痛患者异常情况的能力。
无需机构审查委员会批准和患者知情同意。对306例神经检查结果正常且患有慢性或复发性头痛的患者进行了MR成像检查。患者分为三组:无异常组、轻度异常组和具有可能导致慢性或复发性头痛的重要颅内异常组。还进行了文献综述。计算了MR异常发现频率的99.5%置信上限。
共有169例患者(55.2%)被归入第一组,135例(44.1%)被归入第二组,2例(0.7%)被归入第三组,因为他们在MR成像时有重要临床异常。对比剂增强(n = 195)和重复MR成像(n = 23)均无助于诊断。文献综述显示,除本研究外,之前有两项关于未明确头痛的研究,共包括1036例MR成像结果,其中22例(2.1%)有重要临床结果(99.�%置信上限为3.4%)。发现了12项关于偏头痛的研究,共790例MR成像检查。排除19例复杂性偏头痛患者后,MR成像时重要临床异常频率的99.5%置信上限估计为0.68%。19例复杂性偏头痛患者中有5例(26.3%)的MR图像上发现了重要临床梗死灶。
对于慢性或复发性头痛且神经检查结果正常的患者,MR成像不是一种有效的检查技术。对比增强和重复MR成像均无助于诊断,尽管后一类患者数量较少。