Firrincieli Vincent, Keller Adrienne, Ehrensberger Ryan, Platts-Mills James, Shufflebarger Cindy, Geldmaker Bethany, Platts-Mills Thomas
Department of Medicine, Allergy and Immunology, University of Virginia, Charlottesville, VA 22908, USA.
Pediatr Pulmonol. 2005 Jul;40(1):57-63. doi: 10.1002/ppul.20214.
Asthma is a severe problem among inner city children, and recent evidence suggests that both allergen exposure and lifestyle can impact the disease early in childhood. This study was designed to investigate the association between physical activity and wheezing among a population of inner city children enrolling in Head Start. The parents of children aged 3-5 years responded to a questionnaire (N = 144) to determine the presence and severity of wheezing and asthma. Information was also gathered regarding home environment, food frequency, and presence of other allergic diseases. Serum was obtained to measure total IgE and specific IgE levels to common allergens. Height and weight for body mass index were recorded. Lastly, motion sensor wristwatches (Actiwatch) were worn continuously by a subset of these children (n = 54) for 6 or 7 days. Physical activity measured with the motion sensor was decreased among children with a history of wheezing. The significant differences involved those measures of activity relating to prolonged or sustained physical activity. The correlates of asthma associated with decreased levels of physical activity included: 1) a history of wheezing in the last 12 months, 2) the diagnosis of asthma, and 3) presentation to the emergency room in the last 12 months for wheezing or asthma. In a preschool-age population, decreased physical activity was observed among children with a history of asthma or wheezing. Decreased physical activity could contribute to persistence of asthma or put children at higher risk for obesity and other chronic diseases.
哮喘是城市中心区儿童面临的一个严重问题，最近有证据表明，接触过敏原和生活方式都会在儿童早期对该疾病产生影响。本研究旨在调查参加“启智计划”的城市中心区儿童群体中身体活动与喘息之间的关联。3至5岁儿童的家长对一份问卷（N = 144）做出回应，以确定喘息和哮喘的存在情况及严重程度。还收集了有关家庭环境、食物频率和其他过敏性疾病存在情况的信息。采集血清以测量总IgE和对常见过敏原的特异性IgE水平。记录身高和体重以计算体重指数。最后，这些儿童中的一部分（n = 54）连续佩戴运动传感器手表（活动记录仪）6或7天。有喘息病史的儿童通过运动传感器测量的身体活动减少。显著差异涉及与长时间或持续身体活动相关的活动量度。与身体活动水平降低相关的哮喘相关因素包括：1）过去12个月内有喘息病史，2）哮喘诊断，以及3）过去12个月内因喘息或哮喘到急诊室就诊。在学龄前儿童群体中，有哮喘或喘息病史的儿童身体活动减少。身体活动减少可能导致哮喘持续存在，或使儿童面临更高的肥胖和其他慢性病风险。
