富克斯异色性睫状体炎与眼弓蛔虫病。
Fuchs heterochromic cyclitis and ocular toxocariasis.
作者信息
Teyssot Nicolas, Cassoux Nathalie, Lehoang Phuc, Bodaghi Bahram
机构信息
Department of Ophthalmology, University of Paris VI, Pitié-Salpêtrière Hospital, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
出版信息
Am J Ophthalmol. 2005 May;139(5):915-6. doi: 10.1016/j.ajo.2004.10.054.
PURPOSE
To report the association of Fuchs heterochromic cyclitis (FHC) and ocular toxocariasis in a young adult.
DESIGN
Observational case report.
METHODS
A 26-year-old patient was referred for the management of a unilateral intermediate uveitis associated with a lower peripheral subretinal fibrotic lesion near the pars plana. Diagnosis of FHC was clinically confirmed. Laboratory examination was performed to exclude an infectious condition.
RESULTS
LISA assay detected significant levels of IgG directed against Toxocara canis. Toxoplasmic serology was negative, excluding this differential diagnosis. Other examinations, including complete blood cell count, urinalysis, serum angiotensin-converting enzyme, lysosyme, chest CT scan, and syphilis serology were noncontributive.
CONCLUSIONS
Previous studies have reported on the association of FHC and other parasitic conditions, such as toxoplasmosis but also on herpetic ocular infections. Serologic analysis for toxocariasis may be proposed in patients with FHC and retinal scars in the absence of toxoplasmosis.
目的
报告一名年轻成年人中福氏异色性睫状体炎（FHC）与眼弓蛔虫病的关联。
设计
观察性病例报告。
方法
一名26岁患者因单侧中间葡萄膜炎伴靠近睫状体扁平部的周边视网膜下纤维化病变前来就诊。FHC的诊断经临床确认。进行实验室检查以排除感染性疾病。
结果
LISA检测发现针对犬弓蛔虫的IgG水平显著升高。弓形虫血清学检查为阴性，排除了这一鉴别诊断。其他检查，包括全血细胞计数、尿液分析、血清血管紧张素转换酶、溶菌酶、胸部CT扫描和梅毒血清学检查均无诊断意义。
结论
既往研究报道了FHC与其他寄生虫病（如弓形虫病）以及疱疹性眼部感染的关联。对于患有FHC且有视网膜瘢痕但无弓形虫病的患者，可考虑进行弓蛔虫病的血清学分析。
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