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一名免疫功能正常的57岁男性,眼弓蛔虫病延迟诊断,表现为单眼完全性视网膜脱离。

A delayed diagnosis of ocular toxocariasis presenting as total monocular retinal detachment in an immunocompetent 57-year-old male.

作者信息

Jowsey George W, McLeod Gavin X

机构信息

Department of Internal Medicine, Greenwich Hospital, Yale-New Haven Health System, Greenwich, CT, United States.

出版信息

IDCases. 2023 Apr 11;32:e01764. doi: 10.1016/j.idcr.2023.e01764. eCollection 2023.

Abstract

A healthy 57-year-old man present to outpatient ophthalmological services in southwestern Connecticut with a 16-month history of unilateral periorbital pain, photophobia, and progressively decreasing visual acuity in his left eye. Prior extensive work-up for uveitis in his home state of Mississippi had yielded no etiology for his symptoms, and empiric therapy with glucocorticoid eye drops had not halted their decline. Fundoscopic examination demonstrated total combined retinal detachment of the left eye. Extensive repeat serological and immunological screening was positive for Toxocara immunoglobulin-G, consistent with a diagnosis of ocular toxocariasis, and the patient completed a course of albendazole with stabilization of symptoms. Despite being endemic to the United States, diagnoses of ocular toxocariasis are extremely uncommon, with the majority of cases occurring in young children. This unusual case of ocular toxocariasis in a healthy adult serves to illustrate that significant, irreversible morbidity can result from lack of both clinician and public awareness of this parasitic infection.

摘要

一名57岁的健康男性前往康涅狄格州西南部的门诊眼科就诊,他有16个月的单侧眶周疼痛、畏光病史,且左眼视力逐渐下降。此前,他在密西西比州的家乡因葡萄膜炎接受了广泛检查,但未找到症状的病因,使用糖皮质激素眼药水进行经验性治疗也未能阻止病情恶化。眼底检查显示左眼完全性视网膜脱离合并。广泛的重复血清学和免疫学筛查显示,弓蛔虫免疫球蛋白G呈阳性,符合眼弓蛔虫病的诊断,患者完成了一个疗程的阿苯达唑治疗,症状得到稳定。尽管眼弓蛔虫病在美国是地方性疾病,但眼弓蛔虫病的诊断极为罕见,大多数病例发生在幼儿身上。这例健康成年人患眼弓蛔虫病的不寻常病例表明,由于临床医生和公众对这种寄生虫感染缺乏认识,可能会导致严重的、不可逆转的发病率。

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