Smith R P, Illanes S, Denbow M L, Soothill P W
Fetal Medicine Research Unit, University of Bristol, St Michael's Hospital, Bristol, UK.
Ultrasound Obstet Gynecol. 2005 Jul;26(1):63-6. doi: 10.1002/uog.1883.
Fetal pleural effusions are uncommon, and treatment options for moderate or severe effusions include drainage and thoracoamniotic shunting. However, relatively few records of effusions treated by thoracoamniotic shunting are available in the literature, so our objective was to study the outcome after thoracoamniotic shunting in our unit.
We searched the database of our tertiary fetal medicine unit for all cases of fetal pleural effusion treated by thoracoamniotic shunting between 1997 and 2003 inclusive, and studied the maternal and neonatal records.
Ninety-two cases of fetal pleural effusion were studied, of which 21 had undergone a thoracoamniotic shunt. Sixteen of these 21 fetuses (76%) had associated hydrops, of which seven (44%) survived and, of the five (24%) without associated hydrops, three (60%) survived. There were two procedure-related losses. No shunted cases were associated with abnormal karyotype or proven maternal infection, but it is probable that three cases had been caused by an underlying genetic syndrome.
The survival of fetuses with severe pleural effusions after thoracoamniotic shunting in this study was 48%.
胎儿胸腔积液并不常见,中重度积液的治疗选择包括引流和胸腔羊膜腔分流术。然而,文献中关于胸腔羊膜腔分流术治疗积液的记录相对较少,因此我们的目的是研究我们科室胸腔羊膜腔分流术后的结局。
我们在我们的三级胎儿医学科室数据库中搜索了1997年至2003年(含)期间所有接受胸腔羊膜腔分流术治疗的胎儿胸腔积液病例,并研究了产妇和新生儿记录。
研究了92例胎儿胸腔积液病例,其中21例接受了胸腔羊膜腔分流术。这21例胎儿中有16例(76%)伴有水肿,其中7例(44%)存活;在5例(24%)无相关水肿的胎儿中,3例(60%)存活。有2例与手术相关的死亡病例。没有分流病例与染色体核型异常或确诊的母体感染相关,但可能有3例是由潜在的遗传综合征引起的。
本研究中,严重胸腔积液胎儿经胸腔羊膜腔分流术后的存活率为48%。