Cauley Keith, Dalal Ajay, Olson Beatriz, Onyiuke Hillary
Department of Diagnostic Radiology, University of Connecticut Health Center, Farmington, USA.
Conn Med. 2005 Mar;69(3):143-6.
Lymphocytic hypophysitis (LH) is a rare but increasingly recognized inflammatory disorder of the pituitary, usually associated with pregnancy. Knowledge of this condition is largely anecdotal; the cause, incidence, and natural history are unknown. Cases are usually discovered at biopsy and surgical intervention for a presumptive pituitary neoplasm. Here we describe two cases of lymphocytic hypophysitis. In the first case the patient underwent surgery for presumptive adenoma, and pathology at resection established the diagnosis of lymphocytic hypophysitis. The second case was strongly suspicious for LH by history, endocrine profile, and imaging, and was managed nonoperatively. Though magnetic resonance imaging (MRI) features are not diagnostic, knowledge of imaging features together with clinical history may permit avoidance of surgery.
淋巴细胞性垂体炎（LH）是一种罕见但越来越受到认可的垂体炎症性疾病，通常与妊娠有关。关于这种疾病的了解大多来自个案报道；其病因、发病率和自然病程尚不清楚。病例通常在对疑似垂体肿瘤进行活检和手术干预时被发现。在此，我们描述两例淋巴细胞性垂体炎病例。第一例患者因疑似腺瘤接受手术，切除时的病理检查确诊为淋巴细胞性垂体炎。第二例根据病史、内分泌检查结果和影像学表现高度怀疑为LH，未进行手术治疗。虽然磁共振成像（MRI）特征不具有诊断性，但了解影像学特征并结合临床病史可能避免手术。
