Bouché Nicolas, Yellin Ayelet, Snedden Wayne A, Fromm Hillel
Institut National de la Recherche Agronomique, Institut Jean-Pierre Bourgin, Laboratoire de Biologie Cellulaire, 78026 Versailles, France.
Annu Rev Plant Biol. 2005;56:435-66. doi: 10.1146/annurev.arplant.56.032604.144224.
Calmodulin CaM is the most prominent Ca2+ transducer in eukaryotic cells, regulating the activity of numerous proteins with diverse cellular functions. Many features of CaM and its downstream targets are similar in plants and other eukaryotes. However, plants possess a unique set of CaM-related proteins, and several unique CaM target proteins. This review discusses recent progress in identifying plant-specific CaM-binding proteins and their roles in response to biotic and abiotic stresses and development. The review also addresses aspects emerging from recent structural studies of CaM interactions with target proteins relevant to plants.
钙调蛋白(CaM)是真核细胞中最显著的Ca2+信号转导蛋白,可调节众多具有不同细胞功能的蛋白质的活性。在植物和其他真核生物中,CaM及其下游靶点的许多特征是相似的。然而,植物拥有一组独特的与CaM相关的蛋白质,以及几种独特的CaM靶蛋白。本文综述了在鉴定植物特异性CaM结合蛋白及其在应对生物和非生物胁迫以及发育过程中的作用方面的最新进展。本文还讨论了最近关于CaM与植物相关靶蛋白相互作用的结构研究中出现的一些方面。