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外阴癌放疗后腹股沟血管肉瘤

Groin angiosarcoma following radiotherapy for vulvar cancer.

作者信息

Sanz Clara, Moreno Fernando, Armas Alvaro, Casado Antonio, Castillo M C

机构信息

Gynecology Department, Hospital La Paz, Madrid, Spain.

出版信息

Gynecol Oncol. 2005 May;97(2):677-80. doi: 10.1016/j.ygyno.2004.12.061.

Abstract

BACKGROUND

Angiosarcomas account for less than 2% of all sarcomas. However, they represent 15% of radiotherapy-induced sarcomas, usually associated to the treatment for breast cancer, cervical cancer, and lymphomas.

CASE REPORT

We report the case of a 56-year-old patient who developed a soft tissue angiosarcoma in the right groin 25 years after receiving radiotherapy for vulvar cancer. To our knowledge, this is the second case reported of a soft tissue angiosarcoma after radiotherapy for a vulvar cancer.

CONCLUSION

Postradiation sarcoma must be considered in patients with a history of a previous tumor when a soft tissue mass is seen in the previously irradiated field, especially if the latent period is more than 3 or 5 years. The correct histologic interpretation of such lesions is important because it may result in early identification of the secondary malignancy and may contribute to better management and improved prognosis.

摘要

背景

血管肉瘤占所有肉瘤的比例不到2%。然而,它们占放疗诱发肉瘤的15%,通常与乳腺癌、宫颈癌和淋巴瘤的治疗相关。

病例报告

我们报告一例56岁患者,其在外阴癌放疗25年后,右侧腹股沟出现软组织血管肉瘤。据我们所知,这是第二例报道的外阴癌放疗后发生的软组织血管肉瘤。

结论

既往有肿瘤病史的患者,若在先前放疗区域出现软组织肿块,尤其是潜伏期超过3年或5年时,必须考虑放疗后肉瘤。对此类病变进行正确的组织学解读很重要,因为这可能有助于早期识别继发性恶性肿瘤,并有助于更好地管理和改善预后。

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