Okada H, Tsubura A, Senzaki H, Morii S
Dept. of Pathology, Kansai Med. Univ.
Gan No Rinsho. 1990 Nov;36(14):2497-501.
Presented is the case of a 63-year-old woman who developed a cutaneous angiosarcoma of the hip after receiving adjuvant radiation therapy for a squamous cell carcinoma of the uterine cervix after a hysterectomy. The time lapse between the radiation therapy and the occurrence of the angiosarcoma was 15 years, and its systemic metastasis was seen on autopsy. This autopsy was carried out 26 years after the patient had received the initial irradiation and no recurrence of the uterine cancer was found. Factor involved in the etiology of an angiosarcoma are discussed, and 34 previously reported cases of a postirradiation angiosarcoma are reviewed.
本文报告了一例63岁女性病例,该患者在子宫切除术后因子宫颈鳞状细胞癌接受辅助放疗后发生了臀部皮肤血管肉瘤。放疗与血管肉瘤发生之间的时间间隔为15年,尸检发现有全身转移。此次尸检是在患者首次接受放疗26年后进行的,未发现子宫癌复发。文中讨论了血管肉瘤病因中的相关因素,并回顾了34例先前报道的放疗后血管肉瘤病例。