Lake Richard A, Robinson Bruce W S
Tumour Immunology Group, School of Medicine and Pharmacology, Western Australian Institute for Medical Research, Perth, 6009, Australia.
Nat Rev Cancer. 2005 May;5(5):397-405. doi: 10.1038/nrc1613.
This article discusses how recent data have altered the way we understand how dying tumour cells, particularly those killed by chemotherapy, engage with antitumour immune responses. These data have significant implications for the development of new protocols combining chemotherapy with immunotherapy, indicating an exciting potential for therapeutic synergy with general applicability to many cancer types.
本文讨论了近期的数据如何改变了我们对垂死肿瘤细胞，特别是那些被化疗杀死的肿瘤细胞，与抗肿瘤免疫反应相互作用方式的理解。这些数据对将化疗与免疫疗法相结合的新方案的开发具有重要意义，表明了具有广泛适用于多种癌症类型的治疗协同作用的令人兴奋的潜力。
