Halic Mario, Becker Thomas, Frank Joachim, Spahn Christian M T, Beckmann Roland
Institute of Biochemistry, Charité, University Medical School Berlin, Monbijoustrasse 2, 10117 Berlin, Germany.
Nat Struct Mol Biol. 2005 May;12(5):467-8. doi: 10.1038/nsmb933. Epub 2005 May 1.
The ribosomal protein L30e is an indispensable component of the eukaryotic 80S ribosome, where it is part of the large (60S) ribosomal subunit. Here, we determined the localization of L30e in the cryo-EM map of the 80S wheat germ (wg) ribosome at a resolution of 9.5 A. L30e is part of the interface between large and small subunits, where it dynamically participates in the formation of the two intersubunit bridges eB9 and B4.
核糖体蛋白L30e是真核生物80S核糖体不可或缺的组成部分，它是大（60S）核糖体亚基的一部分。在这里，我们在分辨率为9.5埃的80S小麦胚芽（wg）核糖体的冷冻电镜图中确定了L30e的定位。L30e是大小亚基之间界面的一部分，它动态参与两个亚基间桥eB9和B4的形成。
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