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改进小口径血管移植物:从内皮细胞内衬的应用到组织工程血管的构建。

Improving small-diameter vascular grafts: from the application of an endothelial cell lining to the construction of a tissue-engineered blood vessel.

作者信息

Heyligers J M M, Arts C H P, Verhagen H J M, de Groot Ph G, Moll F L

机构信息

Department of Vascular Surgery, University Medical Center, 3508 GA Utrecht, The Netherlands.

出版信息

Ann Vasc Surg. 2005 May;19(3):448-56. doi: 10.1007/s10016-005-0026-0.

DOI:10.1007/s10016-005-0026-0
PMID:15864472
Abstract

One of the main reasons why vascular reconstruction with synthetic small-diameter grafts has limited success is the absence of endothelial cells. To improve the outcome of nonvenous vascular bypass surgery, cell seeding of vascular grafts and other tissue-engineering techniques were developed. In this article, an overview is given of the artificial blood vessel as an alternative for venous vascular bypass surgery.

摘要

使用合成小口径移植物进行血管重建成功率有限的主要原因之一是缺乏内皮细胞。为了改善非静脉血管搭桥手术的效果,人们开发了血管移植物的细胞接种和其他组织工程技术。本文概述了人工血管作为静脉血管搭桥手术替代物的情况。

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Ann Vasc Surg. 2005 May;19(3):448-56. doi: 10.1007/s10016-005-0026-0.
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