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[下肢闭塞性血栓性脉管炎患者治疗中的外科药物治疗方面]

[Surgical-drug therapy aspects of the treatment of patients with obliterating thromboangiitis of the lower limbs].

作者信息

Gervaziev V B, Bykov V M, Khorev N G, Fust V I, Lepilov A V

出版信息

Grud Serdechnososudistaia Khir. 1992(1-2):25-30.

PMID:1586515
Abstract

Standard operative interventions (thromboendarterectomy, (autovenous shunt) in patients with thromboangiitis obliterans of the lower limbs produce a poor effect. This is explained both by a poor initial condition of the draining channels and by advancement of the primary thromboangitic affection of the vascular wall in the zone of the intervention with its development into a stenotic-occlusive process. The use of some technical (operative) innovations, particularly postoperative arterial infusion of suspended forms of immunosuppresive agents (hydrocortisone, Kenalog), increased essentially the efficacy of restorative operations on the vessels with a high level of limb preservation and patency of the vessels which had been operated on.

摘要

标准手术干预(血栓内膜切除术、下肢血栓闭塞性脉管炎患者的自体静脉分流术)效果不佳。这既归因于引流通道的初始状况较差,也归因于干预区域血管壁原发性血栓性血管病变的进展及其发展为狭窄闭塞性病变。使用一些技术(手术)创新方法,尤其是术后动脉输注悬浮形式的免疫抑制剂(氢化可的松、去炎松),显著提高了血管修复手术的疗效,肢体保留水平较高,且手术血管保持通畅。

相似文献

1
[Surgical-drug therapy aspects of the treatment of patients with obliterating thromboangiitis of the lower limbs].[下肢闭塞性血栓性脉管炎患者治疗中的外科药物治疗方面]
Grud Serdechnososudistaia Khir. 1992(1-2):25-30.
2
[Regional drug microemboli in the treatment of patients with thromboangiitis obliterans of the lower extremities].[区域药物微栓塞治疗下肢血栓闭塞性脉管炎患者]
Khirurgiia (Mosk). 1990 May(5):67-71.
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[Use of regional perfusion in the treatment of arterial occlusive diseases of the lower extremities].[区域灌注在下肢动脉闭塞性疾病治疗中的应用]
Vestn Khir Im I I Grek. 1990 Aug;145(8):36-9.
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[Current news in the pharmacological and surgical treatment of chronic, peripheral, obliterating arterial diseases of the lower limbs].[下肢慢性、周围性、闭塞性动脉疾病的药物及手术治疗的当前进展]
Clin Ter. 1974 Aug 15;70(3):281-91.
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[Intraarterial thrombolytic therapy in obliterative thromboangiitis of the lower extremities].[下肢闭塞性血栓性脉管炎的动脉内溶栓治疗]
Khirurgiia (Mosk). 1993 Feb(2):26-32.
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[Therapeutic acquisitions on chronic obliterating peripheral arterial diseases of the lower limbs].
Minerva Med. 1976 May 19;67(25):1648-55.
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Zhonghua Wai Ke Za Zhi. 1992 Nov;30(11):656-8, 698-9.
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引用本文的文献

1
Omentum autotransplantation in thromboangiitis obliterans: report of three cases.大网膜自体移植治疗血栓闭塞性脉管炎:附3例报告
Surg Today. 1999;29(1):86-90. doi: 10.1007/BF02482978.