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抑郁症状可预测1型糖尿病青少年的住院情况。

Depressive symptoms predict hospitalization for adolescents with type 1 diabetes mellitus.

作者信息

Stewart Sunita M, Rao Uma, Emslie Graham J, Klein Diane, White Perrin C

机构信息

Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8589, USA.

出版信息

Pediatrics. 2005 May;115(5):1315-9. doi: 10.1542/peds.2004-1717.

Abstract

OBJECTIVE

To examine the role of self-reported depressive symptoms in predicting hospitalization for complications of diabetes mellitus over a period of up to 2 years.

STUDY DESIGN

Two hundred thirty-one adolescent outpatients (age range: 11-18 years) with type 1 diabetes completed the Center for Epidemiological Studies Depression Scale, a self-report measure of depressive symptoms. Glycosylated hemoglobin levels were also assessed, to account for this known predictor of hospitalization. With survival analysis methods, hospitalizations for medical complications that occurred up to 2 years after this assessment were recorded.

RESULTS

After controlling for age, gender, socioeconomic status, and glycosylated hemoglobin levels at baseline, the odds ratio for prediction offered by Center for Epidemiological Studies Depression Scale scores above the cutoff point (12 for boys and 22 for girls) was 2.58 (95% confidence interval: 1.12-5.98).

CONCLUSIONS

Young people with type 1 diabetes who show high levels of depressive symptoms are at increased risk for hospitalization for disease complications. Interventions aimed at improving their depressive symptoms may result in positive health outcomes, as well as improved quality of life.

摘要

目的

研究自我报告的抑郁症状在预测长达2年的糖尿病并发症住院情况中的作用。

研究设计

231名1型糖尿病青少年门诊患者(年龄范围:11 - 18岁)完成了流行病学研究中心抑郁量表,这是一种自我报告的抑郁症状测量方法。还评估了糖化血红蛋白水平,以考量这一已知的住院预测因素。采用生存分析方法,记录了此次评估后长达2年发生的医疗并发症住院情况。

结果

在控制了年龄、性别、社会经济地位和基线糖化血红蛋白水平后,流行病学研究中心抑郁量表得分高于临界值(男孩为12分,女孩为22分)的预测比值比为2.58(95%置信区间:1.12 - 5.98)。

结论

抑郁症状水平高的1型糖尿病青少年因疾病并发症住院的风险增加。旨在改善其抑郁症状的干预措施可能会带来积极的健康结果以及生活质量的提高。

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