Boeke A J P, van Bergen J E A M, Morré S A, van Everdingen J J E
VU Medisch Centrum, Van der Boechorststraat 7, 1081 BT Amsterdam.
Ned Tijdschr Geneeskd. 2005 Apr 16;149(16):878-84.
To determine the rate of PID in women with genital Chlamydia trachomatis infection.
Systematic literature review.
MEDLINE and EMBASE were searched over the years 1975-2003 using the keywords 'Chlamydia trachomatis', 'complication', 'pelvic (inflammatory disease)', 'PID', 'endometritis', 'adnexitis', and 'salpingitis'. The reference lists ofthe articles retrieved were checked for other relevant publications. The PID complication rate was determined, as were the characteristics of the study populations and the validity of the diagnostic methods and outcome measures used.
9 prospective studies were identified. The rate of PID in women with a genital C. trachomatis infection varied between o and 72%. Asymptomatic women who were diagnosed with C. trachomatis infection in general screening had the lowest rate of PID: 0-4%. PID occurred in 12-30% of symptomatic women or women with a higher risk of having an STD (e.g. visitor of an STD clinic, double-infection with gonorrhoea, high risk assessed by questionnaire, having a partner with symptomatic C. trachomatis infection). Women who underwent legal abortion had the highest rate of PID (27-72%).
The PID rate in women with C. trachomatis varied considerably. Risk depended on whether the infection was symptomatic and the prior probability of having an STD.
确定生殖器沙眼衣原体感染女性的盆腔炎（PID）发病率。
系统文献综述。
使用关键词“沙眼衣原体”“并发症”“盆腔（炎症性疾病）”“PID”“子宫内膜炎”“附件炎”和“输卵管炎”检索1975年至2003年期间的MEDLINE和EMBASE数据库。检查检索到的文章的参考文献列表以查找其他相关出版物。确定了PID并发症发生率、研究人群的特征以及所使用诊断方法和结局指标的有效性。
共识别出9项前瞻性研究。生殖器沙眼衣原体感染女性的PID发病率在0%至72%之间。在一般筛查中被诊断为沙眼衣原体感染的无症状女性的PID发病率最低：0%至4%。PID发生在12%至30%的有症状女性或性传播疾病（STD）风险较高的女性中（例如性病门诊就诊者、淋病双重感染、通过问卷调查评估为高风险、伴侣有症状性沙眼衣原体感染）。接受合法堕胎的女性的PID发病率最高（27%至72%）。
沙眼衣原体感染女性的PID发病率差异很大。风险取决于感染是否有症状以及患性传播疾病的先验概率。
