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微粒的行波介电泳

Traveling-wave dielectrophoresis of microparticles.

作者信息

Hagedorn R, Fuhr G, Müller T, Gimsa J

机构信息

Department of Biology, Humboldt-University of Berlin, Germany.

出版信息

Electrophoresis. 1992 Jan-Feb;13(1-2):49-54. doi: 10.1002/elps.1150130110.

DOI:10.1002/elps.1150130110
PMID:1587254
Abstract

The traveling-wave-induced linear transfer of dielectric particles like living cells and artificial objects of microscopic dimensions is analyzed. It is shown that the electrode geometries must correspond to particle sizes to allow an effective manipulation of particles immersed in weakly electrolytic solutions by high frequency traveling waves. The theoretical model elaborated in this paper is in good agreement with experimental results obtained in microfabricated chambers of linearly arranged electrodes. It explains the behavior of homogeneous cellulose spheres as well as that of membrane-covered pine polls. The traveling-wave-driven electrodes are described by a superposition of time-dependent point charges. Subsequently, each of these point charges has to be considered as polarizing the dielectric particle and interacting with the polarized particle. This results in forces which effectively translocate the particle.

摘要

分析了像活细胞和微观尺寸的人造物体这样的介电粒子在行波作用下的线性转移。结果表明,电极几何形状必须与粒子尺寸相对应,以便通过高频行波有效操纵浸没在弱电解质溶液中的粒子。本文阐述的理论模型与在微制造的线性排列电极腔室中获得的实验结果高度吻合。它解释了均匀纤维素球体以及膜覆盖的松树花粉粒的行为。行波驱动电极由随时间变化的点电荷叠加来描述。随后,这些点电荷中的每一个都必须被视为使介电粒子极化并与极化粒子相互作用。这会产生有效地使粒子移位的力。

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