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[波斯尼亚和黑塞哥维那人间Q热传播的流行病学调查]

[Epidemiological investigations transmisssion of Q fever among humans in Bosnia and Herzegovina].

作者信息

Puvacić Sandra, Dizdarević Zehra, Zvizdić Sukrija, Tandir Salih, Aliković Ibrahim, Celiks Sukrija

机构信息

Medicinski Fakultet Univerziteta u Sarajevu.

出版信息

Med Arh. 2005;59(2):118-20.

PMID:15875477
Abstract

Appearance of an acute disease by Coxiella burnetii in humans in Bosnia and Herzegovina is very big epidemiological problem because incidence rate is among the highest incidence rates in Europe. Incidence rate of Q fever in Federation Bosnia and Herzegovina was very high during 1998. year 5.68% and the highest in 2000, with 115 diseases with acute clinical form of the disease and incidence rate of 6.95%. The incubation period varied from 9 to 28 days. Real incidence rate because of asymptomatic appearance of the disease is very much higher, at least 40-50 times higher. Chronic infection with Coxiella burnetii has been the most common developed as infectious endocarditis, which is the hardest complication. The researches of mode of transmission Q fever in humans showed that this disease spreads in epidemic and sporadic form in Bosnia and Herzegovina. In the period 1998-2003 year, there were 373 cases of Q fever, among them 265 or 71,05% cases epidemic transmission, and 108 or 28,95% cases sporadic. The research of outbreaks of Q fever showed that appearance of Q fever is statistical significant with risk factors at 266 cases of disease. The mode of transmission in 107 cases was the most probably across inhalation of infected aerosols.

摘要

在波斯尼亚和黑塞哥维那,人类感染伯纳特柯克斯体引发急性疾病是一个非常严重的流行病学问题,因为其发病率位居欧洲最高之列。1998年,波斯尼亚和黑塞哥维那联邦的Q热发病率非常高,为5.68%,2000年最高,有115例急性临床病例,发病率为6.95%。潜伏期为9至28天。由于该疾病无症状表现,实际发病率要高得多,至少高出40至50倍。伯纳特柯克斯体慢性感染最常发展为感染性心内膜炎,这是最严重的并发症。对人类Q热传播方式的研究表明,在波斯尼亚和黑塞哥维那,这种疾病以流行和散发形式传播。在1998 - 2003年期间,共有373例Q热病例,其中265例(占71.05%)为流行传播,108例(占28.95%)为散发。对Q热疫情的研究表明,在266例病例中,Q热的出现与危险因素具有统计学意义。在107例病例中,最可能的传播方式是吸入受感染的气溶胶。

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