Skokić Fahrija, Nevatinović Enida
Klinika za Ginekologiju i Akuserstvo, Univerzitetski Klinicki Centar Tuzla, Trnovac.
Med Arh. 2005;59(2):124-7.
of this work is to show epidemiological and clinical characteristics of congenital anomalies in Tuzla Canton, Bosnia and Herzegovina.
Retrospective analysis of 41 395 labours in Ob & Gyn Clinic University Clinical Centre, Tuzla, from Jan 1995 to Dec 2003. Diagnosis of congenital anomalies was performing on the basis of clinical, ultrasound examination, CAT scan and cariotype.
In the eight years period we have registered 647 live born both genders with congenital anomalies on the birth, with incidence 1:63.97 and prevalence 15.62 on 1000 live born. Most frequently we had hearth congenital anomalies (22.10%) with prevalence of 3.45%. Chromosomal aberrations--Sy Down we had in 83 cases with incidence 1:498.7. Age structure of mothers was between 16 to 42 years, with average age 29,85 (SD +/- 2). Sufficient but not optimal number of controls during pregnancy (8-10) we have only in 8.19% of mothers. Rate between genders was 1:1,27 in favour of female newborns which is significantly different from general population with rate 1,08-1 in favour of male newborns in Tuzla Canton. We have a few options for operative treatment (5.71%) especially in centres with low possibilities for postoperative care and therapy and consequently high mortality (25.96%).
Congenital anomalies are great problem for health care in Tuzla Canton, so we urge to salvation of this problem at the state level.
本研究旨在展示波斯尼亚和黑塞哥维那图兹拉州先天性异常的流行病学和临床特征。
对1995年1月至2003年12月期间图兹拉大学临床中心妇产科诊所的41395例分娩进行回顾性分析。先天性异常的诊断基于临床、超声检查、计算机断层扫描和核型分析。
在这八年期间,我们登记了647例出生时患有先天性异常的活产婴儿,发病率为1:63.97,每1000例活产婴儿中的患病率为15.62。最常见的是心脏先天性异常(22.10%),患病率为3.45%。我们发现83例染色体畸变——唐氏综合征,发病率为1:498.7。母亲的年龄结构在16至42岁之间,平均年龄为29.85岁(标准差±2)。只有8.19%的母亲在孕期进行了足够但并非最佳数量的检查(8 - 10次)。性别比例为1:1.27,有利于女婴,这与图兹拉州一般人群中有利于男婴的1.08:1的比例有显著差异。我们有一些手术治疗选择(5.71%),特别是在术后护理和治疗可能性较低且死亡率较高(25.96%)的中心。
先天性异常是图兹拉州医疗保健面临的重大问题,因此我们敦促在国家层面解决这一问题。