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[图兹拉州地区的严重先天性心脏病]

[Critical congenital heart diseases in Tuzla Canton area].

作者信息

Begić Hidajeta

机构信息

Klinika za Diecije Bolesti, Univerzitetski Klinicki Centar Tuzla.

出版信息

Med Arh. 2006;60(3):162-5.

Abstract

Critical congenital heart diseases (CHD) represent extensive and complex possibilities changes of morphology and homodynamic on the heart, which vital jeopardize child at the time of birth so as at the first weeks of its life or at the first months of its life too. The purpose of this study is to determine frequency, structure and the mode of medical treatment critical UAS in the Tuzla Canton area to harmonies with experiences and results we have reached in order to treat children who have congenital heart disease. There was discovered CHD in the 493 (8,15 per 1000 live-born) from 60.493 live-born children in Tuzla Canton area during the 10-year period start at 01.01.1995. Critical congenital heart disease was discovered in 142 children what represent total prevalence of 2,35 per 1000 live-born children. Yearly prevalence was pretty consistent in observed period of the time and it was from 1,36 to 3,24 per 1000 live born children. The most frequent UAS was complete atrio ventricular canal, which has proved in the 22,4% critical UAS. The more then one-third (36,6 %) children with critical UAS have had extra cardiac anomalies and syndromes. The balloon septostomy was performed in only two of our patients, in 41 (28,8 %) cardiac surgery was performed. Only one of the children underwent surgery in the neonatal period. In 8 patients who were no surgery treated developed pulmonary hypertension, one of them had bacterial endocarditic. Of the total 142 children with critical CHD 99 (69,7%) died. The 92 of them died before surgery, 7 of them died after the surgery; 3 of the 7 in the early after surgery period; 4 of the 7 died because of complications in a later period. Timely discovering critical UAS in Tuzla Canton area is failure in the area prenatal diagnosis. The treatment of patients is inappropriate and without possibilities of emergency invasive cardiac treatment and surgical treatment.

摘要

重症先天性心脏病(CHD)表现为心脏形态和血液动力学广泛而复杂的变化,在出生时以及出生后的头几周或头几个月对儿童的生命构成严重威胁。本研究的目的是确定图兹拉州地区重症先天性心脏病的发病率、结构和治疗方式,以便与我们在治疗先天性心脏病患儿方面所取得的经验和结果相协调。在1995年1月1日开始的10年期间,图兹拉州地区60493名活产儿童中有493名(每1000名活产儿中有8.15名)被发现患有CHD。142名儿童被发现患有重症先天性心脏病,占每1000名活产儿中2.35名的总患病率。在观察期内,年患病率相当稳定,每1000名活产儿中为1.36至3.24名。最常见的先天性心脏病是完全性房室通道,在重症先天性心脏病中占22.4%。超过三分之一(36.6%)患有重症先天性心脏病的儿童有心脏外异常和综合征。我们只有两名患者进行了球囊房间隔造口术,41名(28.8%)进行了心脏手术。只有一名儿童在新生儿期接受了手术。在8名未接受手术治疗的患者中出现了肺动脉高压,其中一名患有细菌性心内膜炎。在142名患有重症CHD的儿童中,99名(69.7%)死亡。其中92名在手术前死亡,7名在手术后死亡;7名中有3名在手术后早期死亡;7名中有4名在后期因并发症死亡。在图兹拉州地区及时发现重症先天性心脏病是产前诊断领域的失败。对患者的治疗不当,且没有紧急侵入性心脏治疗和手术治疗的可能性。

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