Nayana Prabha P, Serane Tiroumourougane V, Nalini P, Mahadevan S
Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Dhanvantri Nagar, Pondicherry, India.
Indian J Pediatr. 2005 Apr;72(4):293-5. doi: 10.1007/BF02724006.
To assess the relationship between Modified Glasgow Coma Scale, its components, brain stem reflexes and long term functional outcome in children with acute non-traumatic coma.
MGCS and brainstem reflexes were assessed at 6 hourly intervals for 72 hours from the time of admission. The children were followed up regularly and functional outcome was assessed at the end of 9 months. The lowest score of the MGCS and worst brain stem reflexes were used for the analysis.
Higher total MGCS score and verbal response score had a significant positive correlation with better functional outcome as measured by GOS and intelligence quotient. There was no association between the language function and the initial MGCS, its components and brain stem reflexes. Lower verbal response (P = 0.005) was the only factor that was found to be individually associated with poorer long term GOS score and intelligence quotient by multivariate linear regression analysis.
In the long term prediction of outcome in acute non-traumatic coma, MGCS is not useful. However, verbal response, a component of MGCS, correlates well with long term functional outcome and intelligence quotient.
评估改良格拉斯哥昏迷量表（Modified Glasgow Coma Scale）及其各组成部分、脑干反射与急性非创伤性昏迷患儿长期功能转归之间的关系。
从入院时起，每6小时对改良格拉斯哥昏迷量表和脑干反射进行评估，持续72小时。对患儿进行定期随访，并在9个月末评估功能转归。分析采用改良格拉斯哥昏迷量表的最低得分和最差脑干反射情况。
改良格拉斯哥昏迷量表总分及言语反应得分越高，与采用格拉斯哥预后评分（GOS）和智商评估的更好功能转归呈显著正相关。语言功能与初始改良格拉斯哥昏迷量表、其各组成部分及脑干反射之间无关联。多因素线性回归分析发现，较低的言语反应（P = 0.005）是唯一与较差的长期格拉斯哥预后评分和智商单独相关的因素。
在急性非创伤性昏迷的长期预后预测中，改良格拉斯哥昏迷量表并无用处。然而，改良格拉斯哥昏迷量表的组成部分之一——言语反应，与长期功能转归和智商密切相关。
