正常大鼠神经细胞外基质主要成分的超微结构定位
Ultrastructural localization of the major components of the extracellular matrix in normal rat nerve.
作者信息
Lorimier P, Mezin P, Labat Moleur F, Pinel N, Peyrol S, Stoebner P
机构信息
Laboratoire de Pathologie Cellulaire, CHUR, Grenoble, France.
出版信息
J Histochem Cytochem. 1992 Jun;40(6):859-68. doi: 10.1177/40.6.1588030.
PMID:1588030
Abstract
In this study we determined the ultrastructural distribution of the various components of the extracellular matrix (laminin, fibronectin, Type I, III, and IV collagens) of the normal peripheral nerve in adult rat. The localization of these macromolecules was investigated in basement membranes as well as in different areas of epi-, peri-, and endoneurium, by use of a pre-embedding immunoperoxidase method.
摘要
在本研究中，我们确定了成年大鼠正常周围神经细胞外基质（层粘连蛋白、纤连蛋白、I型、III型和IV型胶原蛋白）各成分的超微结构分布。采用包埋前免疫过氧化物酶法，研究了这些大分子在基底膜以及神经外膜、神经束膜和神经内膜不同区域的定位。
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