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[在剥脱综合征(PEX)高发人群中的白内障合并PEX综合征患者。临床发现以及形态学和手术特征]

[Cataract patients with pseudoexfoliation (PEX) syndrome among a population with high prevalence of PEX. Clinical findings and morphological and surgical characteristics].

作者信息

Bialasiewicz A A, Wali U, Shenoy R, Al-Saeidi R

机构信息

Department of Ophthalmology and School of Ophthalmic Technicians, Sultan Qaboos University College of Medicine and Health Sciences, Muscat, Oman.

出版信息

Ophthalmologe. 2005 Dec;102(12):1181-5. doi: 10.1007/s00347-005-1227-1.

Abstract

BACKGROUND

Cataracts are the most frequent treatable cause of noninfectious blindness in Oman. Therefore, in 2002 a study was performed at our department of ophthalmology to evaluate cataract patients for pseudoexfoliation.

METHODS

In a prospective comparative cohort study, 370 age-related cataract eyes out of an evaluable population of 498 cataracts were evaluated by biomicroscopy, confocal corneal analysis, and electron microscopy and followed up after 6 months.

RESULTS

Of 370 age-related cataracts without glaucomas 171 had PEX. Preoperative manifestations were 89 subluxations, 15 vitreous prolapses, 6 ciliolenticular blocks, and 7 intravitreal dislocations. In 40 Omani cataract eyes without PEX the endothelial cell count was normal compared to the age-matched US norm and corneal thickness was less than Caucasians, but more than Afro-Americans.

CONCLUSIONS

This study reports on a high incidence and frequent preoperative complications (68%) of the surgical cataract cases in an Arabic population. The development of serious complications and blindness is related to the duration of the disease and the lack of timely surgery.

摘要

背景

白内障是阿曼非感染性失明最常见的可治疗病因。因此,2002年我们眼科进行了一项研究,以评估白内障患者是否患有假性剥脱综合征。

方法

在一项前瞻性比较队列研究中,对498例可评估的白内障患者中的370只年龄相关性白内障眼进行了生物显微镜检查、共焦角膜分析和电子显微镜检查,并在6个月后进行了随访。

结果

在370只无青光眼的年龄相关性白内障眼中,171只患有假性剥脱综合征。术前表现为89例晶状体半脱位、15例玻璃体脱垂、6例睫状晶状体阻滞和7例玻璃体内脱位。在40只无假性剥脱综合征的阿曼白内障眼中,与年龄匹配的美国正常水平相比,内皮细胞计数正常,角膜厚度小于白种人,但大于非裔美国人。

结论

本研究报告了阿拉伯人群白内障手术病例的高发病率和频繁的术前并发症(68%)。严重并发症和失明的发生与疾病持续时间和缺乏及时手术有关。

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