Yaegashi Makito, Jean Raymonde, Zuriqat Muqdad, Noack Sigrid, Homel Peter
St. Luke's-Roosevelt Hospital Center/Columbia University College of Physicians and Surgeons, New York, NY 10019, USA.
J Intensive Care Med. 2005 May-Jun;20(3):147-54. doi: 10.1177/0885066605275314.
This was a retrospective chart review of consecutive obese patients admitted to the medical intensive care unit. Patients were divided into 2 groups: mild to moderately obese (group 1, body mass index =30-40 kg/m(2)) and morbidly obese (group 2, body mass index >40 kg/m(2)). Acute Physiology and Chronic Health Evaluation II scores were not significantly different between the 2 groups. Morbidly obese patients (group 2) had higher rates of mortality and nursing home admission. They also showed higher rates of intensive care unit complications including sepsis, nosocomial pneumonia, acute respiratory distress syndrome, catheter infection, tracheostomy, and acute renal failure. Their median length of mechanical ventilation was longer (2 days, range 2-12 vs 9 days, range 1-37,P = .009). In a logistic regression analysis, morbid obesity remained a significant predictor of death or disposition to nursing home even after controlling for age (P = .019, odds ratio = 7.60, 95% confidence interval = 1.39-41.6). Morbidly obese patients (body mass index >40 kg/m(2)) admitted to intensive care units have higher rates of mortality, nursing home admission, and intensive care unit complications and have longer stays in the intensive care unit and time on mechanical ventilation.
这是一项对入住医学重症监护病房的连续性肥胖患者进行的回顾性病历审查。患者被分为两组:轻度至中度肥胖(第1组,体重指数=30-40kg/m²)和病态肥胖(第2组,体重指数>40kg/m²)。两组之间的急性生理与慢性健康状况评估II评分无显著差异。病态肥胖患者(第2组)的死亡率和入住疗养院率较高。他们还表现出较高的重症监护病房并发症发生率,包括败血症、医院获得性肺炎、急性呼吸窘迫综合征、导管感染、气管切开术和急性肾衰竭。他们的机械通气中位时长更长(2天,范围2-12天 vs 9天,范围1-37天,P = 0.009)。在逻辑回归分析中,即使在控制年龄后,病态肥胖仍然是死亡或入住疗养院的显著预测因素(P = 0.019,比值比 = 7.60,95%置信区间 = 1.39-41.6)。入住重症监护病房的病态肥胖患者(体重指数>40kg/m²)死亡率、入住疗养院率和重症监护病房并发症发生率较高,在重症监护病房的停留时间和机械通气时间更长。