Georgesco M, Reynes J, Pons F, Janbon F, Cadilhac J
Laboratoire d'électromyographie, hôpital Gui-de-Chauliac, France.
Neurophysiol Clin. 1992 Mar;22(1):51-60. doi: 10.1016/s0987-7053(05)80007-3.
In 5 acquired-immunodeficiency syndrome (AIDS) cases without peripheral neuropathy, we observed myogen clinical signs (diffuse amyotrophy of lower limbs or cramps) or an isolated increase in seric enzyme (LDH, CK). EMG abnormalities were observed in all cases: spontaneous activities (fibrillations and positive sharp waves) in 5 cases, myogenic signs in 2 case. Muscular biopsies were normal in 3 cases and showed myopathic changes in 1 case and polymyositis in another case. Antidystrophin and antilaminin antibodies reactions were altered in 1 case. The spontaneous activities together with these modifications could be in favour of a lesion at the membrane level.
在5例无周围神经病变的获得性免疫缺陷综合征（AIDS）患者中，我们观察到肌原性临床体征（下肢弥漫性肌萎缩或痉挛）或血清酶（乳酸脱氢酶、肌酸激酶）单独升高。所有病例均观察到肌电图异常：5例出现自发活动（纤颤和正锐波），2例出现肌原性体征。3例肌肉活检正常，1例显示肌病改变，另1例显示多发性肌炎。1例抗肌萎缩蛋白和抗层粘连蛋白抗体反应改变。这些自发活动以及这些改变可能提示膜水平存在病变。
