Kleinkauf H, van Liempt H, Palissa H, von Döhren H
Institut für Biochemie und Molekulare Biologie, Berlin, FRG.
Naturwissenschaften. 1992 Apr;79(4):153-62. doi: 10.1007/BF01134432.
The biosynthesis of peptides in nonribosomal systems is accomplished by complex multienzymes. These multienzymes assemble the required template for the construction of each natural product in the form of linearly coupled modules. This organization principle permits the integration of multistep synthetic processes on a single macromolecule.
非核糖体系统中肽的生物合成是由复杂的多酶完成的。这些多酶以线性偶联模块的形式组装构建每种天然产物所需的模板。这种组织原则允许在单个大分子上整合多步合成过程。
