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[非HIV免疫功能低下宿主中马红球菌所致坏死性肺炎。病例报告及文献复习]

[Necrotizing pneumonia due to Rhodococcus equi in non HIV immunocompromised host. Case report and review].

作者信息

Rabagliati Ricardo, Morales Arturo, Baudrand René, Jorquera Jorge, Oddó David, García Patricia, Carmona M Cecilia, Cisternas Marcela, Huete Alvaro

机构信息

Departamento de Medicina Interna, Escuela de Medicina, Pontificia Universidad Católica de Chile.

出版信息

Rev Chilena Infectol. 2005 Jun;22(2):155-60. Epub 2005 May 12.

PMID:15891796
Abstract

Rhodococcus equi, is a grampositive intracellular bacillus, that causes infection mainly in immunocompromised hosts. We report the case of a 52 years old woman, with a systemic lupus erythematosus and a progressive 10 months evolution with cough, dyspnea, mucous-purulent sputum, occasionally hemoptysis, intermittent fever, and weight loss of 10%. With partial response to antibiotic treatment, radiological evolution of thoracic scanners evidenced the development of multiple bilateral areas of consolidation, some of them nodular. Percutaneous thoracic biopsy showed characteristic histology and microbiological analysis yielded the identification of Rhodococcus equi in both bronchoalveolar lavage and pulmonary biopsy. She received prolonged bi-associated antibiotic treatment with good clinical and radiological response. This agent must be considered in the study of immunocompromised patients that present with a prolonged evolution of pneumonia.

摘要

马红球菌是一种革兰氏阳性细胞内杆菌,主要引起免疫功能低下宿主的感染。我们报告一例52岁女性病例,该患者患有系统性红斑狼疮,病程进展10个月,伴有咳嗽、呼吸困难、黏液脓性痰、偶有咯血、间歇性发热,体重减轻10%。抗生素治疗有部分反应,胸部扫描仪的影像学进展显示双侧出现多个实变区域,其中一些呈结节状。经皮肺活检显示出特征性组织学表现,微生物学分析在支气管肺泡灌洗和肺活检中均鉴定出马红球菌。她接受了长期联合抗生素治疗,临床和影像学反应良好。在研究出现肺炎长期病程的免疫功能低下患者时,必须考虑到这种病原体。

相似文献

1
[Necrotizing pneumonia due to Rhodococcus equi in non HIV immunocompromised host. Case report and review].[非HIV免疫功能低下宿主中马红球菌所致坏死性肺炎。病例报告及文献复习]
Rev Chilena Infectol. 2005 Jun;22(2):155-60. Epub 2005 May 12.
2
A pulmonary mass caused by Rhodococcus equi infection in a renal transplant recipient.一名肾移植受者因马红球菌感染导致肺部肿块。
Nat Clin Pract Nephrol. 2008 Jul;4(7):398-403. doi: 10.1038/ncpneph0833. Epub 2008 May 27.
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Cytologic appearance of Rhodococcus equi in bronchoalveolar lavage specimens. A case report.支气管肺泡灌洗标本中马红球菌的细胞学表现。病例报告。
Acta Cytol. 1995 Jan-Feb;39(1):111-3.
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[Rhodococcus equi pneumonia in patients with immunodeficiency].免疫缺陷患者的马红球菌肺炎
Ned Tijdschr Geneeskd. 1994 Dec 24;138(52):2587-90.
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Rhodococcus equi: fatal pneumonia in a patient without AIDS.马红球菌:一名无艾滋病患者的致命性肺炎
Heart Lung. 1994 Nov-Dec;23(6):519-20.
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Rhodococcus equi infection.马红球菌感染。
Lancet Infect Dis. 2010 May;10(5):350-9. doi: 10.1016/S1473-3099(10)70068-2.
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[Rhodococcus equi pneumonia in patients with HIV infection: report of 2 cases and review of the literature].[HIV感染患者的马红球菌肺炎:2例报告及文献复习]
Enferm Infecc Microbiol Clin. 1996 Mar;14(3):177-80.
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Poststenotic cavitating pneumonia due to Rhodococcus equi in HIV infection.HIV感染患者中由马红球菌引起的狭窄后空洞性肺炎。
AIDS. 1996 Mar;10(3):339-40. doi: 10.1097/00002030-199603000-00015.
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[Rhodococcus equi pneumonia in an HIV+ patient: An uncommon association].[一名HIV阳性患者的马红球菌肺炎:一种罕见的关联]
Rev Port Pneumol. 2007 Sep-Oct;13(5):703-9.
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Rhodococcus equi pneumonia.马红球菌肺炎
Semin Respir Infect. 1997 Mar;12(1):57-60.

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