Rabagliati Ricardo, Morales Arturo, Baudrand René, Jorquera Jorge, Oddó David, García Patricia, Carmona M Cecilia, Cisternas Marcela, Huete Alvaro
Departamento de Medicina Interna, Escuela de Medicina, Pontificia Universidad Católica de Chile.
Rev Chilena Infectol. 2005 Jun;22(2):155-60. Epub 2005 May 12.
Rhodococcus equi, is a grampositive intracellular bacillus, that causes infection mainly in immunocompromised hosts. We report the case of a 52 years old woman, with a systemic lupus erythematosus and a progressive 10 months evolution with cough, dyspnea, mucous-purulent sputum, occasionally hemoptysis, intermittent fever, and weight loss of 10%. With partial response to antibiotic treatment, radiological evolution of thoracic scanners evidenced the development of multiple bilateral areas of consolidation, some of them nodular. Percutaneous thoracic biopsy showed characteristic histology and microbiological analysis yielded the identification of Rhodococcus equi in both bronchoalveolar lavage and pulmonary biopsy. She received prolonged bi-associated antibiotic treatment with good clinical and radiological response. This agent must be considered in the study of immunocompromised patients that present with a prolonged evolution of pneumonia.
马红球菌是一种革兰氏阳性细胞内杆菌,主要引起免疫功能低下宿主的感染。我们报告一例52岁女性病例,该患者患有系统性红斑狼疮,病程进展10个月,伴有咳嗽、呼吸困难、黏液脓性痰、偶有咯血、间歇性发热,体重减轻10%。抗生素治疗有部分反应,胸部扫描仪的影像学进展显示双侧出现多个实变区域,其中一些呈结节状。经皮肺活检显示出特征性组织学表现,微生物学分析在支气管肺泡灌洗和肺活检中均鉴定出马红球菌。她接受了长期联合抗生素治疗,临床和影像学反应良好。在研究出现肺炎长期病程的免疫功能低下患者时,必须考虑到这种病原体。