Zhu Hong, Guo Yongzheng, Chen Hongchao, Ni Lingmei, Zhu Biao, Qu Tingting
Infection Control Department, the First Affiliated Hospital, Zhejiang University School of Medicine, Hang Zhou, Zhe Jiang, People's Republic of China.
The Department of Infectious Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hang Zhou, Zhe Jiang, People's Republic of China.
Infect Drug Resist. 2025 Apr 23;18:2021-2027. doi: 10.2147/IDR.S517190. eCollection 2025.
is a rare opportunistic Gram-positive bacterium that primarily affects immunocompromised individuals, particularly those with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). The infection often presents as a multisystem, disseminated disease with rapid progression and high mortality if not promptly diagnosed and treated. We report the case of a 34-year-old male AIDS patient who developed pulmonary infection due to . Cultures from bronchoalveolar lavage fluid, metagenomic next-generation sequencing (mNGS), and bronchoscopic brushing all indicated infection with . Following combined anti-infective treatment, the pulmonary infection was controlled, and his condition improved. Clinicians should be alert to the possibility of infection in AIDS patients, emphasizing early diagnosis and targeted therapy to improve patient outcomes.
是一种罕见的机会性革兰氏阳性细菌，主要影响免疫功能低下的个体，特别是那些患有人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）的人。如果不及时诊断和治疗，感染通常表现为多系统、播散性疾病，进展迅速且死亡率高。我们报告了一例34岁男性艾滋病患者因 发生肺部感染的病例。支气管肺泡灌洗 fluid、宏基因组下一代测序（mNGS）和支气管镜刷检的培养均表明感染了 。经过联合抗感染治疗，肺部感染得到控制，他的病情有所改善。临床医生应警惕艾滋病患者发生 感染的可能性，强调早期诊断和针对性治疗以改善患者预后。
原文中“bronchoalveolar lavage fluid”未翻译完整，“fluid”可译为“液体” ；且文中有部分内容未明确写出，用“ ”代替了，你可补充完整后再让我翻译，以得到更准确的译文 。
