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加那利群岛单峰骆驼中与伊氏锥虫感染相关的流产和高新生儿死亡率疫情。

An outbreak of abortions and high neonatal mortality associated with Trypanosoma evansi infection in dromedary camels in the Canary Islands.

作者信息

Gutierrez C, Corbera J A, Juste M C, Doreste F, Morales I

机构信息

Department of Animal Medicine and Surgery, Veterinary Faculty, University of Las Palmas, 3416, Arucas, Las Palmas, Canary Islands, Spain.

出版信息

Vet Parasitol. 2005 Jun 10;130(1-2):163-8. doi: 10.1016/j.vetpar.2005.02.009. Epub 2005 Apr 7.

Abstract

Trypanosoma evansi was diagnosed for the first time in the Canary Islands (Spain) in 1998 in a dromedary camel. Seroprevalences of 4.8% up to 9% have been observed using different diagnostic methods. Affected animals have been treated but the dissemination of the disease is unknown. This article presents an outbreak of abortions and high neonatal mortality attributable to T. evansi infection in camels as well as the clinical assessment of the affected animals. The patients were diagnosed by routine checking (three pregnant animals), after abortion (five dams), or after delivered premature or weak calves (eight dams). At clinical examination, 2 out of 16 affected animals showed moderate signs of chronic form, particularly hyporexia and intolerance to exercise. The aborted fetuses were aged 6-8 months of gestation, approximately. The main laboratorial findings were regenerative anemia (haemolytic anemia), lymphocytic and monocytic leukocytosis, hyperproteinemia, hyperglobulinemia, hypoglycaemia, serum urea increased and serum iron decreased. Treatment using trypanocidal drug (Cymelarsan) resulted highly effective. Massive treatment would be recommended in the entire camel population in the Canary Islands (less than 2000 animals), as therapeutic or preventive measure, in order to control and to achieve an eventual eradication of the disease.

摘要

1998年,在西班牙加那利群岛的一头单峰骆驼中首次诊断出伊氏锥虫。使用不同诊断方法观察到的血清阳性率为4.8%至9%。已对受感染动物进行治疗,但疾病的传播情况尚不清楚。本文介绍了一起由伊氏锥虫感染导致骆驼流产和高新生仔畜死亡率的疫情,以及对受感染动物的临床评估。这些病例是通过常规检查(3头怀孕动物)、流产后(5头母畜)或产下早产或体弱犊牛后(8头母畜)确诊的。临床检查时,16头受感染动物中有2头表现出中度慢性症状,特别是食欲减退和不耐运动。流产胎儿的妊娠龄约为6 - 8个月。主要实验室检查结果为再生性贫血(溶血性贫血)、淋巴细胞和单核细胞增多、高蛋白血症、高球蛋白血症、低血糖、血清尿素升高和血清铁降低。使用杀锥虫药物(美拉胂醇)治疗效果显著。为了控制并最终根除该病,建议对加那利群岛的所有骆驼(不到2000头)进行大规模治疗,作为治疗或预防措施。

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