• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

赛米胂治疗苏丹骆驼自然慢性伊氏锥虫感染的疗效

Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan.

作者信息

Musa M M, Abdoon A M, Nasir B T, Salim Y I, Abdel-Rahman A Y, Shommein A M

机构信息

Tsetse and Trypanosomiasis Control Department, Central Veterinary Research Administration, Khartoum, Soudan.

出版信息

Rev Elev Med Vet Pays Trop. 1994;47(4):397-400.

PMID:7770663
Abstract

The efficacy of Cymelarsan, administered by intramuscular (i/m) injection in the treatment of chronic cases of camel trypanosomosis due to Trypanosoma evansi, was tested under controlled laboratory conditions. It was confirmed that Cymelarsan is a safe drug for use in dromedary camels when administered i/m at dose rates of 0.25 or 0.50 mg/kg body weight. During the 90 days post-treatment no relapses occurred at either dose rate. Hence, the drug was found to be fully effective against the chronic form of the natural disease. A dose of 0.25 mg/kg body weight of Cymelarsan given i/m is recommended.

摘要

在可控的实验室条件下,对通过肌肉注射给予 Cymelarsan 治疗因伊氏锥虫引起的骆驼慢性锥虫病的疗效进行了测试。已证实,当以 0.25 或 0.50 毫克/千克体重的剂量通过肌肉注射给药时,Cymelarsan 是一种用于单峰骆驼的安全药物。在治疗后的 90 天内,两种剂量率均未出现复发情况。因此,发现该药物对自然疾病的慢性形式完全有效。建议肌肉注射给予 0.25 毫克/千克体重的 Cymelarsan 剂量。

相似文献

1
Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan.赛米胂治疗苏丹骆驼自然慢性伊氏锥虫感染的疗效
Rev Elev Med Vet Pays Trop. 1994;47(4):397-400.
2
Efficacy of RM110, a novel trypanocide, in the treatment of Trypanosoma evansi infections in camels.新型杀锥虫剂RM110治疗骆驼伊氏锥虫感染的疗效
Trop Anim Health Prod. 1989 Nov;21(4):223-6. doi: 10.1007/BF02261092.
3
Trypanosoma evansi infection in mainland Spain.在西班牙大陆感染伊氏锥虫。
Vet Parasitol. 2010 Jan 20;167(1):74-6. doi: 10.1016/j.vetpar.2009.09.050. Epub 2009 Oct 7.
4
Parasitological, Serological and Molecular Prevalence of Trypanosoma evansi among Arabian Camels (Camelus dromedaries) with Evaluation of Antitrypanosomal Drugs.寄生虫学、血清学和分子学方法评估抗锥虫药物对感染伊氏锥虫的阿拉伯单峰驼(骆驼属骆驼种)的流行率
Acta Parasitol. 2024 Mar;69(1):465-470. doi: 10.1007/s11686-023-00770-2. Epub 2024 Jan 8.
5
Preliminary efficacy trial of Cymelarsan, a novel trypanocide, in camels naturally infected with Trypanosoma evansi in Kenya.
Acta Trop. 1992 Feb;50(3):271-3. doi: 10.1016/0001-706x(92)90084-b.
6
Preliminary observations on the efficacy of mel Cy (Cymelarsan) in domestic animals infected with stocks of Trypanosoma brucei brucei and T.b. evansi.关于美拉胂醇( Cymelarsan )对感染布氏布氏锥虫和伊氏锥虫家畜的疗效的初步观察
Trop Med Parasitol. 1992 Dec;43(4):226-8.
7
Evaluation of the efficacy of melarsenoxyde cysteamine (Cymelarsan) in treatment of camels experimentally infected with Trypanosoma evansi using antigen trapping enzyme-linked immunosorbent assay.使用抗原捕获酶联免疫吸附测定法评估美拉胂氧半胱胺(Cymelarsan)对实验性感染伊氏锥虫的骆驼的治疗效果。
J Vet Pharmacol Ther. 1995 Dec;18(6):468-70. doi: 10.1111/j.1365-2885.1995.tb00628.x.
8
Trypanosoma vivax is the second leading cause of camel trypanosomosis in Sudan after Trypanosoma evansi.在苏丹,间日锥虫是继伊氏锥虫之后骆驼锥虫病的第二大病因。
Parasit Vectors. 2017 Apr 13;10(1):176. doi: 10.1186/s13071-017-2117-5.
9
An outbreak of abortions and high neonatal mortality associated with Trypanosoma evansi infection in dromedary camels in the Canary Islands.加那利群岛单峰骆驼中与伊氏锥虫感染相关的流产和高新生儿死亡率疫情。
Vet Parasitol. 2005 Jun 10;130(1-2):163-8. doi: 10.1016/j.vetpar.2005.02.009. Epub 2005 Apr 7.
10
Effect of stage of infection with Trypanosoma evansi on Cymelarsan therapy.
Trop Anim Health Prod. 1993 Nov;25(4):223-4. doi: 10.1007/BF02250872.