Yerly Sabine, Kaiser Laurent, Ninet Béatrice
Laboratoire central de virologie Service des maladies infectieuses Département de médecine interne Hôpitaux universitaires de Genève.
Rev Med Suisse. 2005 Mar 30;1(13):887-90, 893-4.
The amplification of nucleic acids is often used for the diagnosis and the follow-up of infectious diseases. The interpretation of PCR results varies according to the pathogens detected, the site of infection and the clinical presentation. PCR tests might be the reference method or only an help for the diagnosis. With the development of antiviral treatments quantitative PCR tests are now essential for the evaluation of treatment efficacy. A discussion with the laboratory is important for the correct interpretation of PCR results.
核酸扩增常用于传染病的诊断和后续监测。聚合酶链反应(PCR)结果的解读因检测到的病原体、感染部位和临床表现而异。PCR检测可能是参考方法,也可能只是诊断的辅助手段。随着抗病毒治疗的发展,定量PCR检测对于评估治疗效果至关重要。与实验室进行讨论对于正确解读PCR结果很重要。