Total and regional body composition and energy expenditure in multiple symmetric lipomatosis.

作者信息

Coin Alessandra, Sergi Giuseppe, Enzi Giuliano, Busetto Luca, Pigozzo Sabrina, Lupoli Lucia, Sträter Dinah, Peruzza Silvia, Inelmen Emine Meral

机构信息

Department of Medical and Surgical Sciences, Geriatrics Division, University of Padova, Via Giustiniani, 2,35128 Padova, Italy.

出版信息

Clin Nutr. 2005 Jun;24(3):367-74. doi: 10.1016/j.clnu.2004.11.012.

DOI:10.1016/j.clnu.2004.11.012

PMID:15896422

Abstract

AIMS

The aim of the present study was to investigate possible alterations in body composition and resting energy expenditure (REE) in type 1 multiple symmetric lipomatosis (MSL).

SUBJECTS AND METHODS

Thirteen men aged from 40 to 78 years affected by type I MSL were compared with 13 healthy control subjects. Fat mass (FM) and fat-free mass (FFM) were determined by DEXA using both standard analysis and specifically for the lipomatous region. REE was measured by indirect calorimetry.

RESULTS

FM was higher in MSL subjects at proximal arm level, but significantly lower at distal leg level than in controls (left 1.63+/-0.55 vs. 2.26+/-0.49 kg, P<0.05; right 1.63+/-0.53 vs. 2.40+/-0.54 kg, P<0.01). Arm FFM was similar in the two groups, while distal leg FFM was significantly lower in MSL cases (left: 7.8+/-1.3 vs. 8.7+/-0.8 kg, P<0.05; right: 8.0+/-1.5 vs. 9.2+/-0.9 kg, P<0.05). FFM strongly correlated with REE (r:0.86;P<0.001). REE, expressed as an absolute value and adjusted for FFM (1830+/-215 vs. 1675+/-120 kcal, P<0.05) was higher in MSL patients.