Spungen A M, Bauman W A, Wang J, Pierson R N
Spinal Cord Damage Research Center, Mount Sinai Medical Center, New York, NY.
Arch Phys Med Rehabil. 1993 Sep;74(9):965-8.
Body composition changes occur with spinal cord injury (SCI): fat-free mass (FFM) decreases and fat mass (FM) increases. FFM has been reported to correlate with resting energy expenditure (REE) in non-SCI individuals. This report addresses the question as to whether REE correlates with measures of FFM in individuals with paraplegia. Twelve males with chronic paraplegia had measurements of total body potassium (TBK), an indicator of lean tissue, by whole body 40K counting, and FFM by dual photon x-ray absorptiometry (FFMDPX). REE was measured using a metabolic cart for exhaled gas analysis. Corrleations between REE and TBK, and REE and FFMDPX were determined. The mean TBK for the group was 2,850 +/- 190 mEq. In all subjects, TBK was below that of expected (predicted from age, height, and weight). For the group this was 34 +/- 0.04% below predicted. The mean FFMDPX was 58.3 +/- 3.3 kg. Following an overnight fast, REE was measured for each subject while in a seated position. The mean REE was 1,855 +/- 70 kcal/day. REE correlates well with both TBK (r = 0.86, p < 0.0005) and FFMDPX (r = 0.80, p < 0.005). In summary, despite losses in metabolically active tissue in individuals with chronic paraplegia, TBK and FFMDPX continue to have a strong relationship with REE. REE (kcal/d) may be used as an indicator of TBK or FFMDPX using the following linear regression equations: TBK (mEq) = 2.28.REE (kcal/d) - 1,377 (SEE = +/- 347) or FFMDPX (kg) = 0.038.REE (kcal/d) - 11.5 (SEE = +/- 7).(ABSTRACT TRUNCATED AT 250 WORDS)
脊髓损伤（SCI）会导致身体成分发生变化：去脂体重（FFM）减少，脂肪量（FM）增加。据报道，在非脊髓损伤个体中，去脂体重与静息能量消耗（REE）相关。本报告探讨了截瘫患者的静息能量消耗是否与去脂体重指标相关这一问题。12名慢性截瘫男性通过全身40K计数测量了作为瘦组织指标的全身钾（TBK），并通过双能X线吸收法（FFMDPX）测量了去脂体重。使用代谢推车进行呼出气体分析来测量静息能量消耗。确定了静息能量消耗与全身钾以及静息能量消耗与去脂体重双能X线吸收法测量值之间的相关性。该组的平均全身钾为2850±190毫当量。在所有受试者中，全身钾低于预期值（根据年龄、身高和体重预测）。该组比预测值低34±0.04%。去脂体重双能X线吸收法测量的平均值为58.3±3.3千克。在禁食一夜后，对每位受试者坐位时的静息能量消耗进行了测量。平均静息能量消耗为1855±70千卡/天。静息能量消耗与全身钾（r = 0.86，p < 0.0005）和去脂体重双能X线吸收法测量值（r = 0.80，p < 0.005）均具有良好的相关性。总之，尽管慢性截瘫患者代谢活跃组织有所减少，但全身钾和去脂体重双能X线吸收法测量值与静息能量消耗仍有很强的关系。静息能量消耗（千卡/天）可使用以下线性回归方程作为全身钾或去脂体重双能X线吸收法测量值的指标：全身钾（毫当量）= 2.28×静息能量消耗（千卡/天） - 1377（标准误 = ±347）或去脂体重双能X线吸收法测量值（千克）= 0.038×静息能量消耗（千卡/天） - 11.5（标准误 = ±7）。（摘要截断于250字）
