Boran Nurettin, Cil Aylin Pelin, Tulunay Gokhan, Ozturkoglu Esmen, Koc Sevgi, Bulbul Dilek, Kose M Faruk
SSK Ankara Maternity and Women's Hospital, Department of Gynecologic Oncology, Etlik, Ankara 06100, Turkey.
Gynecol Oncol. 2005 Jun;97(3):845-51. doi: 10.1016/j.ygyno.2005.03.010.
To evaluate the fertility and recurrence outcomes in women treated with fertility-sparing surgery for borderline ovarian tumors.
A total of 142 patients with borderline ovarian tumors managed surgically from 1993 to 2004 were identified from gynecologic oncology and pathology files of SSK Ankara Maternity and Women's Health Teaching Hospital. Sixty-two of those patients who had conservative surgery were eligible for the study. Information was acquired by retrospective medical record review and patient interview.
The observed recurrence rates after radical and fertility-sparing surgery were 0.0% and 6.5%, respectively. Four patients from the conservative surgery group developed recurrence, in contrast to none of the patients from the non-conservative surgery group. No disease-related deaths occurred in any group. In the conservatively managed group, ten women had successful pregnancies, with a total of 10 live births and 3 abortions. The mean duration of follow-up for the conservative surgery group was 44.3 months (range, 3-128).
Fertility-sparing surgery for borderline ovarian tumors should be considered for women in the reproductive age group who desire preservation of fertility. Recurrence is noted significantly more often after this type of treatment and close follow-up is needed to detect recurrent disease.
评估采用保留生育功能手术治疗交界性卵巢肿瘤的女性的生育能力及复发情况。
从安卡拉SSK妇产与妇女健康教学医院的妇科肿瘤学和病理学档案中，识别出1993年至2004年期间接受手术治疗的142例交界性卵巢肿瘤患者。其中62例行保守手术的患者符合研究条件。通过回顾性病历审查和患者访谈获取信息。
根治性手术和保留生育功能手术后观察到的复发率分别为0.0%和6.5%。保守手术组有4例患者复发，而非保守手术组无患者复发。两组均未发生与疾病相关的死亡。在保守治疗组中，10名女性成功妊娠，共分娩10例活产婴儿，3例流产。保守手术组的平均随访时间为44.3个月（范围3 - 128个月）。
对于希望保留生育功能的育龄期女性，应考虑采用保留生育功能手术治疗交界性卵巢肿瘤。这种治疗后复发更为常见，需要密切随访以检测复发性疾病。
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