[卵巢交界性肿瘤的预后因素及生殖结局：186例患者的回顾性研究]
[Prognostic factors and reproductive outcomes of borderline ovarian tumors: a review of 186 patients].
作者信息
Tao Tao, Cao Dong-yan, Yang Jia-xin, Huang Hui-fang, Wu Ming, Pan Ling-ya, Lang Jing-he, Guo Li-na, Shen Keng
机构信息
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
出版信息
Zhonghua Yi Xue Za Zhi. 2010 May 18;90(19):1304-8.
OBJECTIVE
To determine the clinicopathological characteristics of borderline ovarian tumors and to evaluate their prognostic factors and pregnancy rates/fertility outcomes after conservative surgery.
METHODS
A total of 186 patients with borderline ovarian tumors receiving treatment at our hospital from 1990 to 2007 were retrospectively studied and followed-up post-operatively for at least six months. The effects of clinicopathological characteristics upon recurrence and mortality were analyzed by independent sample t test, Chi-square test, Kaplan-Meier and Cox proportional hazard model.
RESULTS
The median follow-up time was 44 months. One hundred and nine patients underwent conservative surgery and 77 patients underwent radical surgery. Thirty-one relapses were reported. Only 3 died of disease. As demonstrated by multivariate analysis, surgical procedure, stage and pseudomyxoma peritonei were the independent prognostic factors for recurrence.
CONCLUSION
The recurrence rate of conservative surgery is higher than that of radical surgery. However, conservative surgery is safe as it does not result in a higher mortality rate.
目的
确定卵巢交界性肿瘤的临床病理特征，并评估其预后因素以及保守性手术后的妊娠率/生育结局。
方法
回顾性研究1990年至2007年在我院接受治疗的186例卵巢交界性肿瘤患者，并术后随访至少6个月。采用独立样本t检验、卡方检验、Kaplan-Meier法和Cox比例风险模型分析临床病理特征对复发和死亡率的影响。
结果
中位随访时间为44个月。109例患者接受了保守性手术，77例患者接受了根治性手术。报告了31例复发。仅3例死于该疾病。多因素分析表明，手术方式、分期和腹膜假黏液瘤是复发的独立预后因素。
结论
保守性手术的复发率高于根治性手术。然而，保守性手术是安全的，因为它不会导致更高的死亡率。
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