Laird Angela R, Lancaster Jack L, Fox Peter T
Research Imaging Center, University of Texas Health Science Center, San Antonio, TX 78229, USA.
Neuroinformatics. 2005;3(1):65-78. doi: 10.1385/ni:3:1:065.
Human brain mapping is an experimental discipline that establishes structure-function correspondences in the brain through the combined application of experimental psychology, human neuroscience, and noninvasive neuroimaging. A deep and diverse literature on the functional organization of the human brain is emerging, which has pushed neuroimaging squarely into the scientific mainstream. Because of this rapid growth, there is a great need to effectively collect and synthesize the body of literature in this field. The BrainMap database was created in response to this need as an electronic environment for modeling the human brain through quantitative meta-analysis of the brain mapping literature. BrainMap was originally conceived in 1987 and has received continuous funding from 1988 to 2004. During this time, BrainMap has consistently evolved to meet the challenges of an ever-changing field and continues to strive toward higher levels of applicability. In this article, we discuss BrainMap's structure and utility, and relate its progress and development as a neuroinformatics tool.
人类脑图谱是一门实验学科,它通过综合应用实验心理学、人类神经科学和非侵入性神经成像技术,在大脑中建立结构与功能的对应关系。关于人类大脑功能组织的丰富多样的文献正在不断涌现,这使得神经成像技术稳稳地进入了科学主流领域。由于这一快速发展,迫切需要有效地收集和综合该领域的文献资料。为满足这一需求,创建了BrainMap数据库,作为一个通过对脑图谱文献进行定量荟萃分析来模拟人类大脑的电子环境。BrainMap最初构想于1987年,从1988年到2004年一直获得持续资助。在此期间,BrainMap不断发展,以应对不断变化的领域所带来的挑战,并继续朝着更高的适用性水平努力。在本文中,我们将讨论BrainMap的结构和效用,并阐述其作为一种神经信息学工具的进展与发展情况。