钛介导的N-酰基吡咯的烷基化偶联反应

Titanium-mediated alkylative coupling of N-acylpyrroles.

作者信息

Epstein Oleg L, Seo Jung Min, Masalov Nikolai, Cha Jin Kun

机构信息

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, USA.

出版信息

Org Lett. 2005 May 26;7(11):2105-8. doi: 10.1021/ol050352g.

DOI:10.1021/ol050352g

PMID:15901145

Abstract

[reaction: see text]. Inter- and intramolecular titanium-mediated coupling reactions of N-acylpyrroles are reported for convenient functionalization of terminal olefins. Comparison with the Kulinkovich reaction of esters and other carboxylic acid derivatives is also included.

摘要

[反应：见正文]。报道了N-酰基吡咯的分子间和分子内钛介导的偶联反应，用于末端烯烃的便捷官能团化。还包括与酯和其他羧酸衍生物的库林科维奇反应的比较。